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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Identification and validation of a novel predictive signature based on hepatocyte-specific genes in hepatocellular carcinoma by integrated analysis of single-cell and bulk RNA sequencing

Fig. 4

Validation of the expression and prognostic value of specific genes. (A) The volcano plot shows the differential expression of specific genes in hepatocytes and malignant cells. (B) The violin plots displays the expression changes of specific genes under pseudotime analysis. (C) Validation of differential expression of specific genes in normal liver and HCC tissues utilizing TCGA-LIHC, ICGC-LIRI-JP and GSE135631 cohorts. (D) Validation of the survival analysis by using the TCGA-LIHC and ICGC-LIRI-JP cohorts respectively. * P < 0.05, ** P < 0.01, *** P < 0.001, ns: The difference is not significant

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BMC Medical Genomics

ISSN: 1755-8794

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