Table 2 Antimicrobial resistance genes and predicted phenotypic resistance profiles (N = 138)
Antibiotic class | *AMR gene | Resistance due to Mutation | Antibiotics | Resistant-Isolate, n (%) |
|---|---|---|---|---|
Aminoglycoside | aac(3)-IId | - | Gentamicin | 52 (37.7) |
Tetracyclines | tet(A), tet(B), tet(D) | - | Tetracycline | 110 (79.7) |
Folate synthesis-inhibitor | dfrA1, dfrA5, dfrA7, dfrA8, dfrA12, dfrA14 and dfrA17 | - | trimethoprim | 118 (85.5) |
Beta-Lactam | BlaNDM-5, blaOXA-1, blaTEM-1B, blaCTX-M-15 and blaCTX-M-27 | - | Meropenem Amoxicillin/clavunated Ampicillin Ceftriaxone Ceftazidime | 2 (1.4) 41 (29.7) 125 (90.6) 68 (49.3) 68 (49.3) |
Quinolone | qnrS1 | gyrA mutation, parC mutation and parE mutation | Ciprofloxacin Nalidixic acid | 105 (76.1) 100 (72.5) |
Amphenicol | cmlA1, cat, catA1, catA2, catB3 and floR | - | Chloramphenicol | 18 (13.0) |