Table 2 Sample size estimates for GWAS of diabetic retinopathy with power estimates for the individual sites and with combined data
eMERGE site | Estimated number of diabetic retinopathy cases and controls | Power for GWAS, p < 10-8, MAF = .10 OR = 2.5 |
|---|---|---|
Marshfield | 367/569 | .424 |
Northwestern | 150/1262 | .243 |
Mayo | 83/3412 | .101 |
Group Health | 324/667 | .449 |
Vanderbilt | 260/500 | .270 |
Combined | 1184/6410 | .999 |