Table 9 Gene Ontology categories enriched among the genes associated with lifetime glioblastoma survival1
Gene Ontology | Level | Term | P-value | FDR adjusted P-value | Number of genes | Genes |
|---|---|---|---|---|---|---|
Biological process | 3 | aging (GO:0007568) | 2.13E-05 | 1.62E-03 | 3 | Pdcd4, Cdkn2a, Tp53 |
| Â | Â | regulation of biological process (GO:0050789) | 2.77E-04 | 1.50E-02 | 20 | Usf2, Cdkn2a, Ccnb2, Akt2, Tp53, Cdc42, Six6, Jag2, Lin7c, Pdcd4, Csf1, Topors, Spg21, Akt1, Egfr, Sox10, C2, Scn5a, Arhgef4, Cdk2 |
| Â | Â | protein localization (GO:0008104) | 1.49E-03 | 3.77E-02 | 7 | Topors, Akt1, Sar1a, Egfr, Timm23, Tp53, Lin7c |
| Â | Â | cell division (GO:0051301) | 2.04E-03 | 3.88E-02 | 3 | Ccnb2, Cdc42, Cdk2 |
| Â | Â | cell cycle (GO:0007049) | 3.75E-03 | 5.14E-02 | 7 | Pdcd4, Egfr, Cdk2, Cdkn2a, Ccnb2, Tp53, Jag2 |
| Â | Â | nitrogen compound metabolic process (GO:0006807) | 4.06E-03 | 5.14E-02 | 4 | Chst4, Akt1, Egfr, Chi3l1 |
| Â | Â | cell proliferation (GO:0008283) | 8.32E-03 | 8.99E-02 | 6 | Csf1, Topors, Egfr, Cdk2, Tp53, Jag2 |
| Â | Â | death (GO:0016265) | 9.46E-03 | 8.99E-02 | 6 | Akt1, Cdkn2a, Tp53, Jag2, Pdcd4, Topors |
| Â | 4 | cell aging (GO:0007569) | 4.38E-06 | 9.42E-04 | 3 | Pdcd4, Cdkn2a, Tp53 |