Dai C, Holland E: Astrocyte Differentiation States and Glioma Formation. Glioblastoma Multiforme. Edited by: Markert J,DeVita Jr VT,Rosenberg SA,Hellman S.Sudbury, MA. 2005, Jones and Barlett Publishers, 1-1
Google Scholar
Ohgaki H, Dessen P, Jourde B, Horstmann S, Nishikawa T, Di Patre PL, Burkhard C, Schuler D, Probst-Hensch NM, Maiorka PC, Baeza N, Pisani P, Yonekawa Y, Yasargil MG, Lutolf UM, Kleihues P: Genetic pathways to glioblastoma: a population-based study. Cancer Res. 2004, 64 (19): 6892-6899. 10.1158/0008-5472.CAN-04-1337.
CAS
PubMed
Google Scholar
Novakova J, Slaby O, Vyzula R, Michalek J: MicroRNA involvement in glioblastoma pathogenesis. Biochem Biophys Res Commun. 2009, 386 (1): 1-5. 10.1016/j.bbrc.2009.06.034.
CAS
PubMed
Google Scholar
Wrensch M, Minn Y, Chew T, Bondy M, Berger MS: Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro Oncol. 2002, 4 (4): 278-299.
PubMed
PubMed Central
Google Scholar
Butowski N, Chang S: Adult High-Grade Glioma. High-Grade Gliomas Diagnosis and Treatment. Edited by: Barnett GH. Danvers, MA. 2006, Humana Press, 59-1
Google Scholar
Kesari S, Schiff D, Henson JW, Muzikansky A, Gigas DC, Doherty L, Batchelor TT, Longtine JA, Ligon KL, Weaver S, Laforme A, Ramakrishna N, Black PM, Drappatz J, Ciampa A, Folkman J, Kieran M, Wen PY: Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults. Neuro Oncol. 2008, 10 (3): 300-308. 10.1215/15228517-2008-005.
CAS
PubMed
PubMed Central
Google Scholar
McGirt MJ, Than KD, Weingart JD, Chaichana KL, Attenello FJ, Olivi A, Laterra J, Kleinberg LR, Grossman SA, Brem H, Quinones-Hinojosa A: Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme. J Neurosurg. 2009, 110 (3): 583-588. 10.3171/2008.5.17557.
CAS
PubMed
PubMed Central
Google Scholar
Minniti G, Muni R, Lanzetta G, Marchetti P, Enrici RM: Chemotherapy for glioblastoma: current treatment and future perspectives for cytotoxic and targeted agents. Anticancer Res. 2009, 29 (12): 5171-5184.
CAS
PubMed
Google Scholar
Maucort-Boulch D, Baron MH, Pommier P, Weber DC, Mizoe JE, Rochat J, Boissel JP, Balosso J, Tsujii H, Amsallem E: Rationale for carbon ion therapy in high-grade glioma based on a review and a meta-analysis of neutron beam trials. Cancer Radiother. 2010, 14 (1): 34-41.
CAS
PubMed
Google Scholar
Mischel PS, Shai R, Shi T, Horvath S, Lu KV, Choe G, Seligson D, Kremen TJ, Palotie A, Liau LM, Cloughesy TF, Nelson SF: Identification of molecular subtypes of glioblastoma by gene expression profiling. Oncogene. 2003, 22 (15): 2361-2373. 10.1038/sj.onc.1206344.
CAS
PubMed
Google Scholar
Rich JN, Hans C, Jones B, Iversen ES, McLendon RE, Rasheed BK, Dobra A, Dressman HK, Bigner DD, Nevins JR, West M: Gene expression profiling and genetic markers in glioblastoma survival. Cancer Res. 2005, 65 (10): 4051-4058. 10.1158/0008-5472.CAN-04-3936.
CAS
PubMed
Google Scholar
Houillier C, Lejeune J, Benouaich-Amiel A, Laigle-Donadey F, Criniere E, Mokhtari K, Thillet J, Delattre JY, Hoang-Xuan K, Sanson M: Prognostic impact of molecular markers in a series of 220 primary glioblastomas. Cancer. 2006, 106 (10): 2218-2223. 10.1002/cncr.21819.
CAS
PubMed
Google Scholar
Wang L, Wei Q, Wang LE, Aldape KD, Cao Y, Okcu MF, Hess KR, El-Zein R, Gilbert MR, Woo SY, Prabhu SS, Fuller GN, Bondy ML: Survival prediction in patients with glioblastoma multiforme by human telomerase genetic variation. J Clin Oncol. 2006, 24 (10): 1627-1632. 10.1200/JCO.2005.04.0402.
CAS
PubMed
Google Scholar
Krex D, Klink B, Hartmann C, von Deimling A, Pietsch T, Simon M, Sabel M, Steinbach JP, Heese O, Reifenberger G, Weller M, Schackert G, German Glioma Network: Long-term survival with glioblastoma multiforme. Brain. 2007, 130 (Pt 10): 2596-2606.
PubMed
Google Scholar
Dreyfuss JM, Johnson MD, Park PJ: Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers. Mol Cancer. 2009, 8: 71-10.1186/1476-4598-8-71.
PubMed
PubMed Central
Google Scholar
Gyorffy B, Lanczky A, Eklund AC, Denkert C, Budczies J, Li Q, Szallasi Z: An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients. 2009, Breast Cancer Res Treat
Google Scholar
Comincini S, Paolillo M, Barbieri G, Palumbo S, Sbalchiero E, Azzalin A, Russo MA, Schinelli S: Gene expression analysis of an EGFR indirectly related pathway identified PTEN and MMP9 as reliable diagnostic markers for human glial tumor specimens. J Biomed Biotechnol. 2009, 2009: 924565.
PubMed
PubMed Central
Google Scholar
Castells X, Acebes JJ, Boluda S, Moreno-Torres A, Pujol J, Julia-Sape M, Candiota AP, Arino J, Barcelo A, Arus C: Development of a predictor for human brain tumors based on gene expression values obtained from two types of microarray technologies. OMICS. 2010, 14 (2): 157-164. 10.1089/omi.2009.0093.
CAS
PubMed
Google Scholar
Wei KC, Huang CY, Chen PY, Feng LY, Wu TW, Chen SM, Tsai HC, Lu YJ, Tsang NM, Tseng CK, Pai PC, Shin JW: Evaluation of the prognostic value of CD44 in glioblastoma multiforme. Anticancer Res. 2010, 30 (1): 253-259.
CAS
PubMed
Google Scholar
Cancer Genome Atlas Research Network: Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008, 455 (7216): 1061-1068. 10.1038/nature07385.
Google Scholar
TCGA Data Portal. [http://tcga-data.nci.nih.gov/tcga/tcgaHome2.jsp]
Irizarry RA, Gautier L, Bolstad BM, Miller C: Methods for Affymetrix Oligonucleotide Arrays. [http://bioconductor.org/packages/2.5/bioc/html/affy.html]
Beehive. [http://stagbeetle.animal.uiuc.edu/Beehive]
Marko NF, Toms SA, Barnett GH, Weil R: Genomic expression patterns distinguish long-term from short-term glioblastoma survivors: a preliminary feasibility study. Genomics. 2008, 91 (5): 395-406. 10.1016/j.ygeno.2008.01.002.
CAS
PubMed
Google Scholar
Reddy SP, Britto R, Vinnakota K, Aparna H, Sreepathi HK, Thota B, Kumari A, Shilpa BM, Vrinda M, Umesh S, Samuel C, Shetty M, Tandon A, Pandey P, Hegde S, Hegde AS, Balasubramaniam A, Chandramouli BA, Santosh V, Kondaiah P, Somasundaram K, Rao MR: Novel glioblastoma markers with diagnostic and prognostic value identified through transcriptome analysis. Clin Cancer Res. 2008, 14 (10): 2978-2987. 10.1158/1078-0432.CCR-07-4821.
CAS
PubMed
Google Scholar
Bredel M, Scholtens DM, Harsh GR, Bredel C, Chandler JP, Renfrow JJ, Yadav AK, Vogel H, Scheck AC, Tibshirani R, Sikic BI: A network model of a cooperative genetic landscape in brain tumors. JAMA. 2009, 302 (3): 261-275. 10.1001/jama.2009.997.
CAS
PubMed
PubMed Central
Google Scholar
Zhang J, Liu B, Jiang X, Zhao H, Fan M, Fan Z, Lee JJ, Jiang T, Jiang T, Song SW: A systems biology-based gene expression classifier of glioblastoma predicts survival with solid tumors. PLoS One. 2009, 4 (7): e6274-10.1371/journal.pone.0006274.
PubMed
PubMed Central
Google Scholar
KEGG PATHWAY: Glioma - Homo sapiens (humans). [http://www.genome.jp/kegg/pathway/hsa/hsa05214.html]
Cox DR, Oakes D: Analysis of survival data. 1984, London: Chapman and Hall, 1
Google Scholar
NCBI-Gene database. [http://www.ncbi.nlm.nih.gov/gene]
Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT, Harris MA, Hill DP, Issel-Tarver L, Kasarskis A, Lewis S, Matese JC, Richardson JE, Ringwald M, Rubin GM, Sherlock G: Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet. 2000, 25 (1): 25-29. 10.1038/75556.
CAS
PubMed
PubMed Central
Google Scholar
Kanehisa M, Goto S: KEGG: Kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 2000, 28 (1): 27-30. 10.1093/nar/28.1.27.
CAS
PubMed
PubMed Central
Google Scholar
Al-Shahrour F, Minguez P, Tarraga J, Montaner D, Alloza E, Vaquerizas JM, Conde L, Blaschke C, Vera J, Dopazo J: BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments. Nucleic Acids Res. 2006, 34 (Web Server issue): W472-6.
CAS
PubMed
PubMed Central
Google Scholar
Martin A, Ochagavia ME, Rabasa LC, Miranda J, Fernandez-de-Cossio J, Bringas R: BisoGenet: a new tool for gene network building, visualization and analysis. BMC Bioinformatics. 2010, 11: 91-10.1186/1471-2105-11-91.
PubMed
PubMed Central
Google Scholar
Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T: Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003, 13 (11): 2498-2504. 10.1101/gr.1239303.
CAS
PubMed
PubMed Central
Google Scholar
Dumur CI, Ladd AC, Wright HV, Penberthy LT, Wilkinson DS, Powers CN, Garrett CT, DiNardo LJ: Genes involved in radiation therapy response in head and neck cancers. Laryngoscope. 2009, 119 (1): 91-101. 10.1002/lary.20005.
CAS
PubMed
PubMed Central
Google Scholar
Chuang LY, Yang CH, Wu KC, Yang CH: A hybrid feature selection method for DNA microarray data. Comput Biol Med. 2011, 41 (4): 228-237. 10.1016/j.compbiomed.2011.02.004.
CAS
PubMed
Google Scholar
Chuang LY, Yang CS, Li JC, Yang CH: Chaotic genetic algorithm for gene selection and classification problems. OMICS. 2009, 13 (5): 407-420. 10.1089/omi.2009.0007.
CAS
PubMed
Google Scholar
Petrausch U, Martus P, Tonnies H, Bechrakis NE, Lenze D, Wansel S, Hummel M, Bornfeld N, Thiel E, Foerster MH, Keilholz U: Significance of gene expression analysis in uveal melanoma in comparison to standard risk factors for risk assessment of subsequent metastases. Eye (Lond). 2008, 22 (8): 997-1007.
CAS
Google Scholar
Lachenbruch PA, Mickey MR: Estimation of error rates in discriminant analysis. Technometrics. 1968, 10 (1): 1-11. 10.2307/1266219.
Google Scholar
National Cancer Institute: REMBRANDT home page. [http://rembrandt.nci.nih.gov]
Madhavan S, Zenklusen JC, Kotliarov Y, Sahni H, Fine HA, Buetow K: Rembrandt: helping personalized medicine become a reality through integrative translational research. Mol Cancer Res. 2009, 7 (2): 157-167. 10.1158/1541-7786.MCR-08-0435.
CAS
PubMed
PubMed Central
Google Scholar
Delfino KR, Rodriguez-Zas SL, Serão NVL, Southey BR: A Computational Strategy To Identify General And Individualized Genomic Biomarkers. Proceedings of the 6th International Symposium on Bioinformatics Research and Applications: 23-26 May 2010; Storrs, Connecticut. 2010, 31-33.
Google Scholar
National Cancer Institute: Surveillance Epidemiology and End Results. [http://seer.cancer.gov/publications/survival]
Fu Y, Zhang Q, Kang C, Zhang J, Zhang K, Pu P, Wang G, Wang T: Inhibitory effects of adenovirus mediated Akt1 and PIK3R1 shRNA on the growth of malignant tumor cells in vitro and in vivo. Cancer Biol Ther. 2009, 8 (11): 1002-1009. 10.4161/cbt.8.11.8285.
CAS
PubMed
Google Scholar
Welch C, Chen Y, Stallings RL: MicroRNA-34a functions as a potential tumor suppressor by inducing apoptosis in neuroblastoma cells. Oncogene. 2007, 26 (34): 5017-5022. 10.1038/sj.onc.1210293.
CAS
PubMed
Google Scholar
Fre S, Pallavi SK, Huyghe M, Lae M, Janssen KP, Robine S, Artavanis-Tsakonas S, Louvard D: Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine. Proc Natl Acad Sci USA. 2009, 106 (15): 6309-6314. 10.1073/pnas.0900427106.
CAS
PubMed
PubMed Central
Google Scholar
Mullendore ME, Koorstra JB, Li YM, Offerhaus GJ, Fan X, Henderson CM, Matsui W, Eberhart CG, Maitra A, Feldmann G: Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer. Clin Cancer Res. 2009, 15 (7): 2291-2301. 10.1158/1078-0432.CCR-08-2004.
CAS
PubMed
PubMed Central
Google Scholar
Mittal S, Subramanyam D, Dey D, Kumar RV, Rangarajan A: Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis. Mol Cancer. 2009, 8: 128-10.1186/1476-4598-8-128.
PubMed
PubMed Central
Google Scholar
Sim EU, Ang CH, Ng CC, Lee CW, Narayanan K: Differential expression of a subset of ribosomal protein genes in cell lines derived from human nasopharyngeal epithelium. J Hum Genet. 2010, 55 (2): 118-120. 10.1038/jhg.2009.124.
CAS
PubMed
Google Scholar
Alterman RL, Stanley ER: Colony stimulating factor-1 expression in human glioma. Mol Chem Neuropathol. 1994, 21 (2-3): 177-188. 10.1007/BF02815350.
CAS
PubMed
Google Scholar
Sala G, Dituri F, Raimondi C, Previdi S, Maffucci T, Mazzoletti M, Rossi C, Iezzi M, Lattanzio R, Piantelli M, Iacobelli S, Broggini M, Falasca M: Phospholipase Cgamma1 is required for metastasis development and progression. Cancer Res. 2008, 68 (24): 10187-10196. 10.1158/0008-5472.CAN-08-1181.
CAS
PubMed
Google Scholar
Zeng Y, Yang Z, Xu JG, Yang MS, Zeng ZX, You C: Differentially expressed genes from the glioblastoma cell line SHG-44 treated with all-trans retinoic acid in vitro. J Clin Neurosci. 2009, 16 (2): 285-294. 10.1016/j.jocn.2007.11.014.
CAS
PubMed
Google Scholar
Gene Expression Atlas: Summary for AKR1C3 (Homo sapiens). [http://www.ebi.ac.uk/gxa/gene/ENSG00000196139]
Rich JN, Guo C, McLendon RE, Bigner DD, Wang XF, Counter CM: A genetically tractable model of human glioma formation. Cancer Res. 2001, 61 (9): 3556-3560.
CAS
PubMed
Google Scholar
van den Boom J, Wolter M, Kuick R, Misek DE, Youkilis AS, Wechsler DS, Sommer C, Reifenberger G, Hanash SM: Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. Am J Pathol. 2003, 163 (3): 1033-1043. 10.1016/S0002-9440(10)63463-3.
CAS
PubMed
PubMed Central
Google Scholar
Suzuki T, Maruno M, Wada K, Kagawa N, Fujimoto Y, Hashimoto N, Izumoto S, Yoshimine T: Genetic analysis of human glioblastomas using a genomic microarray system. Brain Tumor Pathol. 2004, 21 (1): 27-34. 10.1007/BF02482174.
CAS
PubMed
Google Scholar
Vousden KH, Lane DP: P53 in Health and Disease. Nat Rev Mol Cell Biol. 2007, 8 (4): 275-283. 10.1038/nrm2147.
CAS
PubMed
Google Scholar
Tessema M, Belinsky SA: Mining the epigenome for methylated genes in lung cancer. Proc Am Thorac Soc. 2008, 5 (8): 806-810. 10.1513/pats.200805-045TH.
PubMed
PubMed Central
Google Scholar
Doherty JA, et al: ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study. Cancer Epidemiol Biomarkers Prev. 2010, 19 (1): 245-250. 10.1158/1055-9965.EPI-09-0729.
CAS
PubMed
PubMed Central
Google Scholar
Chan TA, Glockner S, Yi JM, Chen W, Van Neste L, Cope L, Herman JG, Velculescu V, Schuebel KE, Ahuja N, Baylin SB: Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis. PLoS Med. 2008, 5 (5): e114-10.1371/journal.pmed.0050114.
PubMed
PubMed Central
Google Scholar
Gao F, Zhang P, Zhou C, Li J, Wang Q, Zhu F, Ma C, Sun W, Zhang L: Frequent loss of PDCD4 expression in human glioma: possible role in the tumorigenesis of glioma. Oncol Rep. 2007, 17 (1): 123-128.
CAS
PubMed
Google Scholar
Chen Z, Gu J: Immunoglobulin G expression in carcinomas and cancer cell lines. FASEB J. 2007, 21 (11): 2931-2938. 10.1096/fj.07-8073com.
PubMed
Google Scholar
Calogero RA, Cordero F, Forni G, Cavallo F: Inflammation and breast cancer. Inflammatory component of mammary carcinogenesis in ErbB2 transgenic mice. Breast Cancer Res. 2007, 9 (4): 211-10.1186/bcr1745.
PubMed
PubMed Central
Google Scholar
Sun W, Zhang K, Zhang X, Lei W, Xiao T, Ma J, Guo S, Shao S, Zhang H, Liu Y, Yuan J, Hu Z, Ma Y, Feng X, Hu S, Zhou J, Cheng S, Gao Y: Identification of differentially expressed genes in human lung squamous cell carcinoma using suppression subtractive hybridization. Cancer Lett. 2004, 212 (1): 83-93. 10.1016/j.canlet.2004.03.023.
CAS
PubMed
Google Scholar
Martin DN, Boersma BJ, Yi M, Reimers M, Howe TM, Yfantis HG, Tsai YC, Williams EH, Lee DH, Stephens RM, Weissman AM, Ambs S: Differences in the tumor microenvironment between African-American and European-American breast cancer patients. PLoS One. 2009, 4 (2): e4531-10.1371/journal.pone.0004531.
PubMed
PubMed Central
Google Scholar
Liu Y, Su W, Thompson EA, Leitges M, Murray NR, Fields AP: Protein kinase CbetaII regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo. J Biol Chem. 2004, 279 (44): 45556-45563. 10.1074/jbc.M407701200.
CAS
PubMed
Google Scholar
Ferletta M, Uhrbom L, Olofsson T, Ponten F, Westermark B: Sox10 has a broad expression pattern in gliomas and enhances platelet-derived growth factor-B--induced gliomagenesis. Mol Cancer Res. 2007, 5 (9): 891-897. 10.1158/1541-7786.MCR-07-0113.
CAS
PubMed
Google Scholar
Nigro JM, Misra A, Zhang L, Smirnov I, Colman H, Griffin C, Ozburn N, Chen M, Pan E, Koul D, Yung WK, Feuerstein BG, Aldape KD: Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma. Cancer Res. 2005, 65 (5): 1678-1686. 10.1158/0008-5472.CAN-04-2921.
CAS
PubMed
Google Scholar
Pelloski CE, Mahajan A, Maor M, Chang EL, Woo S, Gilbert M, Colman H, Yang H, Ledoux A, Blair H, Passe S, Jenkins RB, Aldape KD: YKL-40 expression is associated with poorer response to radiation and shorter overall survival in glioblastoma. Clin Cancer Res. 2005, 11 (9): 3326-3334. 10.1158/1078-0432.CCR-04-1765.
CAS
PubMed
Google Scholar
Baskar R, Hande MP: A comparative study of protein kinase C activation in gamma-irradiated proliferating and confluent human lung fibroblast cells. J Radiat Res (Tokyo). 2009, 50 (5): 415-423. 10.1269/jrr.08125.
CAS
Google Scholar
Nibbe RK: Systems biology of human colorectal cancer. 2010
Google Scholar
Brennan C, Momota H, Hambardzumyan D, Ozawa T, Tandon A, Pedraza A, Holland E: Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations. PLoS One. 2009, 4 (11): e7752-10.1371/journal.pone.0007752.
PubMed
PubMed Central
Google Scholar
Nindl I, Dang C, Forschner T, Kuban RJ, Meyer T, Sterry W, Stockfleth E: Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling. Mol Cancer. 2006, 5: 30-10.1186/1476-4598-5-30.
PubMed
PubMed Central
Google Scholar
Nutt CL, Mani DR, Betensky RA, Tamayo P, Cairncross JG, Ladd C, Pohl U, Hartmann C, McLaughlin ME, Batchelor TT, Black PM, von Deimling A, Pomeroy SL, Golub TR, Louis DN: Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res. 2003, 63 (7): 1602-1607.
CAS
PubMed
Google Scholar
Trougakos IP, Gonos ES: Clusterin/apolipoprotein J in human aging and cancer. Int J Biochem Cell Biol. 2002, 34 (11): 1430-1448. 10.1016/S1357-2725(02)00041-9.
CAS
PubMed
Google Scholar
Christensen BC, Houseman EA, Poage GM, Godleski JJ, Bueno R, Sugarbaker DJ, Wiencke JK, Nelson HH, Marsit CJ, Kelsey KT: Integrated profiling reveals a global correlation between epigenetic and genetic alterations in mesothelioma. Cancer Res. 2010, 70 (14): 5686-5694. 10.1158/0008-5472.CAN-10-0190.
CAS
PubMed
PubMed Central
Google Scholar
Frederick L, Wang XY, Eley G, James CD: Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res. 2000, 60 (5): 1383-1387.
CAS
PubMed
Google Scholar
Halatsch ME, Schmidt U, Unterberg A, Vougioukas VI: Uniform MDM2 overexpression in a panel of glioblastoma multiforme cell lines with divergent EGFR and p53 expression status. Anticancer Res. 2006, 26 (6B): 4191-4194.
CAS
PubMed
Google Scholar
Razis E, Selviaridis P, Labropoulos S, Norris JL, Zhu MJ, Song DD, Kalebic T, Torrens M, Kalogera-Fountzila A, Karkavelas G, Karanastasi S, Fletcher JA, Fountzilas G: Phase II study of neoadjuvant imatinib in glioblastoma: evaluation of clinical and molecular effects of the treatment. Clin Cancer Res. 2009, 15 (19): 6258-6266. 10.1158/1078-0432.CCR-08-1867.
CAS
PubMed
Google Scholar
Salhia B, Tran NL, Chan A, Wolf A, Nakada M, Rutka F, Ennis M, McDonough WS, Berens ME, Symons M, Rutka JT: The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma. Am J Pathol. 2008, 173 (6): 1828-1838. 10.2353/ajpath.2008.080043.
CAS
PubMed
PubMed Central
Google Scholar
Wang D, Li W, Jiang W, Humphrey LE, Howell GM, Brattain MG: Autocrine TGFalpha expression in the regulation of initiation of human colon carcinoma growth. J Cell Physiol. 1998, 177 (3): 387-395. 10.1002/(SICI)1097-4652(199812)177:3<387::AID-JCP2>3.0.CO;2-L.
CAS
PubMed
Google Scholar
Michael D, Oren M: The p53-Mdm2 module and the ubiquitin system. Semin Cancer Biol. 2003, 13 (1): 49-58. 10.1016/S1044-579X(02)00099-8.
CAS
PubMed
Google Scholar
Carpten JD, Faber AL, Horn C, Donoho GP, Briggs SL, Robbins CM, Hostetter G, Boguslawski S, Moses TY, Savage S, Uhlik M, Lin A, Du J, Qian YW, Zeckner DJ, Tucker-Kellogg G, Touchman J, Patel K, Mousses S, Bittner M, Schevitz R, Lai MH, Blanchard KL, Thomas JE: A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature. 2007, 448 (7152): 439-444. 10.1038/nature05933.
CAS
PubMed
Google Scholar
Lymbouridou R, Soufla G, Chatzinikola AM, Vakis A, Spandidos DA: Down-regulation of K-ras and H-ras in human brain gliomas. Eur J Cancer. 2009, 45 (7): 1294-1303. 10.1016/j.ejca.2008.12.028.
CAS
PubMed
Google Scholar
Wang G, Kang C, Pu P: Increased expression of Akt2 and activity of PI3K and cell proliferation with the ascending of tumor grade of human gliomas. Clin Neurol Neurosurg. 2010, 112 (4): 324-327. 10.1016/j.clineuro.2010.01.003.
PubMed
Google Scholar
Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L, Williams PM, Modrusan Z, Feuerstein BG, Aldape K: Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006, 9 (3): 157-173. 10.1016/j.ccr.2006.02.019.
CAS
PubMed
Google Scholar
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM, Hayes DN, Cancer Genome Atlas Research Network: Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 2010, 17 (1): 98-110. 10.1016/j.ccr.2009.12.020.
CAS
PubMed
PubMed Central
Google Scholar
John T, Black MA, Toro TT, Leader D, Gedye CA, Davis ID, Guilford PJ, Cebon JS: Predicting clinical outcome through molecular profiling in stage III melanoma. Clin Cancer Res. 2008, 14 (16): 5173-5180. 10.1158/1078-0432.CCR-07-4170.
CAS
PubMed
Google Scholar
MacDonald TJ, Pollack IF, Okada H, Bhattacharya S, Lyons-Weiler J: Progression-associated genes in astrocytoma identified by novel microarray gene expression data reanalysis. Methods Mol Biol. 2007, 377: 203-222. 10.1007/978-1-59745-390-5_13.
CAS
PubMed
Google Scholar
Hodgson JG, Yeh RF, Ray A, Wang NJ, Smirnov I, Yu M, Hariono S, Silber J, Feiler HS, Gray JW, Spellman PT, Vandenberg SR, Berger MS, James CD: Comparative analyses of gene copy number and mRNA expression in glioblastoma multiforme tumors and xenografts. Neuro Oncol. 2009, 11 (5): 477-487. 10.1215/15228517-2008-113.
CAS
PubMed
PubMed Central
Google Scholar
Weller M, Felsberg J, Hartmann C, Berger H, Steinbach JP, Schramm J, Westphal M, Schackert G, Simon M, Tonn JC, Heese O, Krex D, Nikkhah G, Pietsch T, Wiestler O, Reifenberger G, von Deimling A, Loeffler M: Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol. 2009, 27 (34): 5743-5750. 10.1200/JCO.2009.23.0805.
CAS
PubMed
Google Scholar
Lagerstedt KK, Kristiansson E, Lonnroth C, Andersson M, Iresjo BM, Gustafsson A, Hansson E, Kressner U, Nordgren S, Enlund F, Lundholm K: Genes with relevance for early to late progression of colon carcinoma based on combined genomic and transcriptomic information from the same patients. Cancer Inform. 2010, 9: 79-91.
CAS
PubMed
PubMed Central
Google Scholar
Ocejo-Garcia M, Baokbah TA, Ashurst HL, Cowlishaw D, Soomro I, Coulson JM, Woll PJ: Roles for USF-2 in lung cancer proliferation and bronchial carcinogenesis. J Pathol. 2005, 206 (2): 151-159. 10.1002/path.1775.
CAS
PubMed
Google Scholar
Bhatti P, Stewart PA, Hutchinson A, Rothman N, Linet MS, Inskip PD, Rajaraman P: Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors. Cancer Epidemiol Biomarkers Prev. 2009, 18 (6): 1841-1848. 10.1158/1055-9965.EPI-09-0197.
CAS
PubMed
PubMed Central
Google Scholar
Soulier J, Clappier E, Cayuela JM, Regnault A, Garcia-Peydro M, Dombret H, Baruchel A, Toribio ML, Sigaux F: HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL). Blood. 2005, 106 (1): 274-286. 10.1182/blood-2004-10-3900.
CAS
PubMed
Google Scholar
Onda T, Uzawa K, Nakashima D, Saito K, Iwadate Y, Seki N, Shibahara T, Tanzawa H: Lin-7C/VELI3/MALS-3: an essential component in metastasis of human squamous cell carcinoma. Cancer Res. 2007, 67 (20): 9643-9648. 10.1158/0008-5472.CAN-07-1911.
CAS
PubMed
Google Scholar
Jenssen TK, Kuo WP, Stokke T, Hovig E: Associations between gene expressions in breast cancer and patient survival. Hum Genet. 2002, 111 (4-5): 411-420. 10.1007/s00439-002-0804-5.
PubMed
Google Scholar
Pavlides S, Tsirigos A, Vera I, Flomenberg N, Frank PG, Casimiro MC, Wang C, Pestell RG, Martinez-Outschoorn UE, Howell A, Sotgia F, Lisanti MP: Transcriptional evidence for the "Reverse Warburg Effect" in human breast cancer tumor stroma and metastasis: similarities with oxidative stress, inflammation, Alzheimer's disease, and "Neuron-Glia Metabolic Coupling". Aging (Albany NY). 2010, 2 (4): 185-199.
CAS
Google Scholar
Cheng W, Jiang Y, Liu C, Shen O, Tang W, Wang X: Identification of aberrant promoter hypomethylation of HOXA10 in ovarian cancer. J Cancer Res Clin Oncol. 2010, 136 (8): 1221-1227. 10.1007/s00432-010-0772-4.
CAS
PubMed
Google Scholar
Thomas G, Jacobs KB, Yeager M, Kraft P, Wacholder S, Orr N, Yu K, Chatterjee N, Welch R, Hutchinson A, Crenshaw A, Cancel-Tassin G, Staats BJ, Wang Z, Gonzalez-Bosquet J, Fang J, Deng X, Berndt SI, Calle EE, Feigelson HS, Thun MJ, Rodriguez C, Albanes D, Virtamo J, Weinstein S, Schumacher FR, Giovannucci E, Willett WC, Cussenot O, Valeri A, Andriole GL, Crawford ED, Tucker M, Gerhard DS, Fraumeni JF, Hoover R, Hayes RB, Hunter DJ, Chanock SJ: Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet. 2008, 40 (3): 310-315. 10.1038/ng.91.
CAS
PubMed
Google Scholar
Hasegawa S, Furukawa Y, Li M, Satoh S, Kato T, Watanabe T, Katagiri T, Tsunoda T, Yamaoka Y, Nakamura Y: Genome-wide analysis of gene expression in intestinal-type gastric cancers using a complementary DNA microarray representing 23,040 genes. Cancer Res. 2002, 62 (23): 7012-7017.
CAS
PubMed
Google Scholar
Madoz-Gurpide J, Canamero M, Sanchez L, Solano J, Alfonso P, Casal JI: A proteomics analysis of cell signaling alterations in colorectal cancer. Mol Cell Proteomics. 2007, 6 (12): 2150-2164. 10.1074/mcp.M700006-MCP200.
CAS
PubMed
Google Scholar
Li HP, Ji JF, Hou KY, Lei YT, Zhao HM, Wang J, Zheng J, Liu JY, Wang MP, Xiao Y, Wang YF, Lu YY, Sun Y: Prediction of recurrence risk in early breast cancer using human epidermal growth factor 2 and cyclin A2. Chin Med J (Engl). 2010, 123 (4): 431-437.
CAS
Google Scholar
Cigognini D, Corneo G, Fermo E, Zanella A, Tripputi P: HIC gene, a candidate suppressor gene within a minimal region of loss at 7q31.1 in myeloid neoplasms. Leuk Res. 2007, 31 (4): 477-482. 10.1016/j.leukres.2006.09.007.
CAS
PubMed
Google Scholar
Rorive S, Maris C, Debeir O, Sandras F, Vidaud M, Bieche I, Salmon I, Decaestecker C: Exploring the distinctive biological characteristics of pilocytic and low-grade diffuse astrocytomas using microarray gene expression profiles. J Neuropathol Exp Neurol. 2006, 65 (8): 794-807. 10.1097/01.jnen.0000228203.12292.a1.
CAS
PubMed
Google Scholar
Kwabi-Addo B, Wang S, Chung W, Jelinek J, Patierno SR, Wang BD, Andrawis R, Lee NH, Apprey V, Issa JP, Ittmann M: Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men. Clin Cancer Res. 2010, 16 (14): 3539-3547. 10.1158/1078-0432.CCR-09-3342.
CAS
PubMed
Google Scholar
Jacinto FV, Ballestar E, Ropero S, Esteller M: Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells. Cancer Res. 2007, 67 (24): 11481-11486. 10.1158/0008-5472.CAN-07-2687.
CAS
PubMed
Google Scholar
Lae M, Ahn EH, Mercado GE, Chuai S, Edgar M, Pawel BR, Olshen A, Barr FG, Ladanyi M: Global gene expression profiling of PAX-FKHR fusion-positive alveolar and PAX-FKHR fusion-negative embryonal rhabdomyosarcomas. J Pathol. 2007, 212 (2): 143-151. 10.1002/path.2170.
CAS
PubMed
Google Scholar
Graham K, de las Morenas A, Tripathi A, King C, Kavanah M, Mendez J, Stone M, Slama J, Miller M, Antoine G, Willers H, Sebastiani P, Rosenberg CL: Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile. Br J Cancer. 2010, 102 (8): 1284-1293. 10.1038/sj.bjc.6605576.
CAS
PubMed
PubMed Central
Google Scholar
Watanabe T, Kobunai T, Toda E, Kanazawa T, Kazama Y, Tanaka J, Tanaka T, Yamamoto Y, Hata K, Kojima T, Yokoyama T, Konishi T, Okayama Y, Sugimoto Y, Oka T, Sasaki S, Ajioka Y, Muto T, Nagawa H: Gene expression signature and the prediction of ulcerative colitis-associated colorectal cancer by DNA microarray. Clin Cancer Res. 2007, 13 (2 Pt 1): 415-420.
CAS
PubMed
Google Scholar
Campbell JM, Lockwood WW, Buys TP, Chari R, Coe BP, Lam S, Lam WL: Integrative genomic and gene expression analysis of chromosome 7 identified novel oncogene loci in non-small cell lung cancer. Genome. 2008, 51 (12): 1032-1039. 10.1139/G08-086.
CAS
PubMed
Google Scholar
Fernandez LP, Milne RL, Pita G, Floristan U, Sendagorta E, Feito M, Aviles JA, Martin-Gonzalez M, Lazaro P, Benitez J, Ribas G: Pigmentation-related genes and their implication in malignant melanoma susceptibility. Exp Dermatol. 2009, 18 (7): 634-642. 10.1111/j.1600-0625.2009.00846.x.
CAS
PubMed
Google Scholar
Schraders M, Jares P, Bea S, Schoenmakers EF, van Krieken JH, Campo E, Groenen PJ: Integrated genomic and expression profiling in mantle cell lymphoma: identification of gene-dosage regulated candidate genes. Br J Haematol. 2008, 143 (2): 210-221. 10.1111/j.1365-2141.2008.07334.x.
CAS
PubMed
Google Scholar
Rohozinski J, Anderson ML, Broaddus RE, Edwards CL, Bishop CE: Spermatogenesis associated retrogenes are expressed in the human ovary and ovarian cancers. PLoS One. 2009, 4 (3): e5064-10.1371/journal.pone.0005064.
PubMed
PubMed Central
Google Scholar
Grade M, Hormann P, Becker S, Hummon AB, Wangsa D, Varma S, Simon R, Liersch T, Becker H, Difilippantonio MJ, Ghadimi BM, Ried T: Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas. Cancer Res. 2007, 67 (1): 41-56. 10.1158/0008-5472.CAN-06-1514.
CAS
PubMed
PubMed Central
Google Scholar
Ganguly A, Shields CL: Differential gene expression profile of retinoblastoma compared to normal retina. Mol Vis. 2010, 16: 1292-1303.
CAS
PubMed
PubMed Central
Google Scholar
Schaeffer DF, Owen DR, Lim HJ, Buczkowski AK, Chung SW, Scudamore CH, Huntsman DG, Ng SS, Owen DA: Insulin-like growth factor 2 mRNA binding protein 3 (IGF2BP3) overexpression in pancreatic ductal adenocarcinoma correlates with poor survival. BMC Cancer. 2010, 10: 59-10.1186/1471-2407-10-59.
PubMed
PubMed Central
Google Scholar
Smith MW, Yue ZN, Geiss GK, Sadovnikova NY, Carter VS, Boix L, Lazaro CA, Rosenberg GB, Bumgarner RE, Fausto N, Bruix J, Katze MG: Identification of novel tumor markers in hepatitis C virus-associated hepatocellular carcinoma. Cancer Res. 2003, 63 (4): 859-864.
CAS
PubMed
Google Scholar
Shirahata M, Iwao-Koizumi K, Saito S, Ueno N, Oda M, Hashimoto N, Takahashi JA, Kato K: Gene expression-based molecular diagnostic system for malignant gliomas is superior to histological diagnosis. Clin Cancer Res. 2007, 13 (24): 7341-7356. 10.1158/1078-0432.CCR-06-2789.
CAS
PubMed
Google Scholar
Ikenaga N, Ohuchida K, Mizumoto K, Yu J, Kayashima T, Hayashi A, Nakata K, Tanaka M: Characterization of CD24 expression in intraductal papillary mucinous neoplasms and ductal carcinoma of the pancreas. 2010, Hum Pathol
Google Scholar
Takeno A, Takemasa I, Doki Y, Yamasaki M, Miyata H, Takiguchi S, Fujiwara Y, Matsubara K, Monden M: Integrative approach for differentially overexpressed genes in gastric cancer by combining large-scale gene expression profiling and network analysis. Br J Cancer. 2008, 99 (8): 1307-1315. 10.1038/sj.bjc.6604682.
CAS
PubMed
PubMed Central
Google Scholar
Kim JH, Kim HN, Lee KT, Lee JK, Choi SH, Paik SW, Rhee JC, Lowe AW: Gene expression profiles in gallbladder cancer: the close genetic similarity seen for early and advanced gallbladder cancers may explain the poor prognosis. Tumour Biol. 2008, 29 (1): 41-49. 10.1159/000132570.
CAS
PubMed
Google Scholar
Chen C, Mendez E, Houck J, Fan W, Lohavanichbutr P, Doody D, Yueh B, Futran ND, Upton M, Farwell DG, Schwartz SM, Zhao LP: Gene expression profiling identifies genes predictive of oral squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev. 2008, 17 (8): 2152-2162. 10.1158/1055-9965.EPI-07-2893.
CAS
PubMed
PubMed Central
Google Scholar
Prapinjumrune C, Morita K, Kuribayashi Y, Hanabata Y, Shi Q, Nakajima Y, Inazawa J, Omura K: DNA amplification and expression of FADD in oral squamous cell carcinoma. J Oral Pathol Med. 2010, 39 (7): 525-532.
CAS
PubMed
Google Scholar
Blaveri E, Brewer JL, Roydasgupta R, Fridlyand J, DeVries S, Koppie T, Pejavar S, Mehta K, Carroll P, Simko JP, Waldman FM: Bladder cancer stage and outcome by array-based comparative genomic hybridization. Clin Cancer Res. 2005, 11 (19 Pt 1): 7012-7022.
CAS
PubMed
Google Scholar
Chevillard S, Ugolin N, Vielh P, Ory K, Levalois C, Elliott D, Clayman GL, El-Naggar AK: Gene expression profiling of differentiated thyroid neoplasms: diagnostic and clinical implications. Clin Cancer Res. 2004, 10 (19): 6586-6597. 10.1158/1078-0432.CCR-04-0053.
CAS
PubMed
Google Scholar
Lau YF, Zhang J: Expression analysis of thirty one Y chromosome genes in human prostate cancer. Mol Carcinog. 2000, 27 (4): 308-321. 10.1002/(SICI)1098-2744(200004)27:4<308::AID-MC9>3.0.CO;2-R.
CAS
PubMed
Google Scholar
Garcia-Munoz R, Panizo C, Bendandi M, Llorente L: Autoimmunity and lymphoma: is mantle cell lymphoma a mistake of the receptor editing mechanism?. Leuk Res. 2009, 33 (11): 1437-1439. 10.1016/j.leukres.2009.05.008.
CAS
PubMed
Google Scholar
Dong S, Nutt CL, Betensky RA, Stemmer-Rachamimov AO, Denko NC, Ligon KL, Rowitch DH, Louis DN: Histology-based expression profiling yields novel prognostic markers in human glioblastoma. J Neuropathol Exp Neurol. 2005, 64 (11): 948-955. 10.1097/01.jnen.0000186940.14779.90.
PubMed
PubMed Central
Google Scholar
Gorringe KL, Ramakrishna M, Williams LH, Sridhar A, Boyle SE, Bearfoot JL, Li J, Anglesio MS, Campbell IG: Are there any more ovarian tumor suppressor genes? A new perspective using ultra high-resolution copy number and loss of heterozygosity analysis. Genes Chromosomes Cancer. 2009, 48 (10): 931-942. 10.1002/gcc.20694.
CAS
PubMed
Google Scholar
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