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Table 1 Characteristics of the individuals included in the replication stages of the study.

From: Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

  PATIENTS WITH IDIOPATHIC DVT CONTROLS
n= 719 719
GEOGRAPHIC ORIGIN, n (%)   
   Lombardy 453 (63) 490 (67)
   Northern Italy other than Lombardy 89 (13) 84 (12)
   Central Italy 30 (4) 20 (3)
   Southern Italy and islands 109 (15) 107 (15)
   Not available 38 (5) 18 (3)
MALE GENDER, n (%) 325 (45) 325 (45)
AGE, mean years (standard deviation) 42.5 (15) 42.5 (14)
PULMONARY EMBOLISM, n (%) 148 (20) /
REFERRED FOR MORE THAN ONE EPISODE, n (%) 167 (23) /
BODY MASS INDEX, kg/m2 25.9 (4.7) 24 (4)
FACTOR V LEIDEN (rs6025) GENOTYPE, n (%)   
   GG 611 (85) 696 (97)
   AG 102 (14) 23 (3)
   AA 6 (1) 0
PROTHROMBIN G20210A (rs1799963) GENOTYPE, n (%)  
   GG 654 (91) 695 (97)
   AG 63 (8) 24 (3)
   AA 2 (1) 0
NATURAL ANTICOAGULANT DEFICIENCIES, n (%)   
   Antithrombin 22 (3) 2 (0.2)
   Protein C 26 (3) 2 (0.2)
   Protein S 30 (4) 10 (1)
LABORATORY MEASUREMENTS, mean (standard deviation)   
   Antithrombin,% 97 (12) 99 (15)
   Protein C, % 102 (27) 105 (22)
   Protein S, % 105 (30) 111 (31)
   Prothrombin time, international normalized ratio 1 (0.16) 0.99 (0.15)
   Activated partial thromboplastin time, ratio 1 (0.1) 1 (0.1)
   Coagulation factor VIII coagulant activity, % 142 (39) 114 (30)
   Fibrinogen coagulant activity, % 304 (72) 291 (63)