Transcriptome signatures in Helicobacter pylori-infected mucosa identifies acidic mammalian chitinase loss as a corpus atrophy marker

Table 1 Information about of all patients included in the study

Age	Gender	Group	Analyses performed¹			Neutrophils²		Mononuclear cells²		Atrophy²		Intestinal metaplasia²
Age	Gender	Group	Array	qPCR	WB	Antrum	Corpus	Antrum	Corpus	Antrum	Corpus	Antrum	Corpus
70	Male	Atr		Yes	Yes	0	1	2	2	1	2	0	0
41	Male	Hp+	Yes			2	1	1	1	1	1	0	1
79	Female	Hp+	Yes			2	1	3	2	2	1	1	0
61	Male	Atr			Yes	0	1	0	2	0	2	0	0
62	Male	Atr	Yes	Yes		0	0	1	1	1	3	2	3
78	Male	Hp-	Yes			1	0	1	1	1	1	2	1
68	Male	Hp+		Yes	Yes	0	1	1	1	0	0	0	0
33	Male	Hp+			Yes	0	0	2	1	0	0	0	0
65	Female	Hp+	Yes	Yes		1	1	2	2	0	0	0	0
60	Female	Hp+		Yes	Yes	0	0	1	1	0	0	0	0
63	Male	Hp-	Yes			0	0	2	0	0	0	0	0
63	Female	Atr		Yes		0	1	1	2	0	2	0	0
81	Female	Atr	Yes			0	0	1	2	0	2	0	1
46	Male	Atr	Yes			1	1	2	2	0	2	1	1
71	Male	Hp-	Yes	Yes		0	0	1	0	0	0	0	0
82	Male	Hp-		Yes	Yes	0	0	0	0	0	0	0	0
55	Male	Hp-		Yes		0	0	0	0	0	0	0	0
42	Female	Atr		Yes	Yes	1	3	2	3	0	2	0	0
67	Female	Hp-		Yes	Yes	0	0	0	0	1	0	0	0
74	Male	Hp+		Yes		2	1	2	2	1	1	1	1
56	Female	Hp+			Yes	0	0	2	0	0	0	0	0

¹The assays performed, using samples from each individual patient, are shown.
²Paraffin-embedded sections were analyzed and scored according to the Updated Sydney system (Am J Surg Path 1996:20:1161), where scores may be judged 0 (absent), 1 (mild), 2 (moderate) and 3 (severe).

ISSN: 1755-8794