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Table 2 SNPs involved in significant interactions. Columns from left to right are: SNP identifier, region in which the SNP is located, gene, Frequencies in the cases, frequencies in the controls, ORs and 95 % of confidence interval (CI), nominal p-value and adjusted p-value

From: Identification of epistatic interactions through genome-wide association studies in sporadic medullary and juvenile papillary thyroid carcinomas

Analysis SNP Region Gene Frequency cases Frequency controls OR [95 % CI] P-value Adjusted p-value
sMTC rs4758915 Intronic CHFR 0.03704 0.02586 1.449 [0.4003–5.243] 0.5702 0.9812
sMTC rs10402530 Downstream AC016582.2 0.1944 0.1897 1.031 [0.5782–1.84] 0.9167 0.9936
sMTC rs7835921 Intronic C8orf37 0.4519 0.5086 0.7966 [0.5008–1.267] 0.3365 0.9669
sMTC rs1287079 Downstream RNU1-55P 0.3019 0.3664 0.7479 [0.4567–1.225] 0.2476 0.9569
jPTC rs2235544 Intronic DIO1 0.4667 0.5043 0.86 [0.487–1.519] 0.6032 0.9696
jPTC rs16876356 Intronic DMGDH 0.1167 0.2308 0.4403 [0.1891–1.025] 0.0518 0.9007
jPTC rs17716031 Intronic RP11-648K4.2 0.1034 0.1336 0.7481 [0.2964–1.888] 0.5379 0.9668
jPTC rs10775207 Intronic LOXL1 0.0167 0.0087 1.932 [0.1723–21.67] 0.5868 0.9668