Figge JJ. Epidemiology of thyroid cancer. In: Wartofsky LVND, editor. Thyroid Cancer: A Comprehensive Guide to Clinical Management. Totowa: Human Press; 1999.
Google Scholar
Randolph GW, Maniar D. Medullary carcinoma of the thyroid. Cancer Control. 2000;7(3):253–61.
CAS
PubMed
Google Scholar
Moline J EC: Multiple Endocrine Neoplasia Type 2. In: SourceGeneReviews® [Internet]. Edited by Pagon RA AM, Ardinger HH, Wallace SE, Amemiya A, Bean LJH, Bird TD, Dolan CR, Fong CT, Smith RJH, Stephens K, editors. Seattle: University of Washington, Seattle; 2005.
Eng C, Clayton D, Schuffenecker I, Lenoir G, Cote G, Gagel RF, et al. The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis. Jama. 1996;276(19):1575–9.
Article
CAS
PubMed
Google Scholar
Fernandez RM, Pecina A, Antinolo G, Navarro E, Borrego S. Analysis of RET polymorphisms and haplotypes in the context of sporadic medullary thyroid carcinoma. Thyroid. 2006;16(4):411–7.
Article
CAS
PubMed
Google Scholar
Landa I, Robledo M. Association studies in thyroid cancer susceptibility: are we on the right track? J Mol Endocrinol. 2011;47(1):R43–58.
Article
CAS
Google Scholar
Ruiz-Llorente S, Montero-Conde C, Milne RL, Moya CM, Cebrian A, Leton R, et al. Association study of 69 genes in the ret pathway identifies low-penetrance loci in sporadic medullary thyroid carcinoma. Cancer Res. 2007;67(19):9561–7.
Article
CAS
PubMed
Google Scholar
Kondo T, Ezzat S, Asa SL. Pathogenetic mechanisms in thyroid follicular-cell neoplasia. Nat Rev Cancer. 2006;6(4):292–306.
Article
CAS
PubMed
Google Scholar
Dottorini ME, Vignati A, Mazzucchelli L, Lomuscio G, Colombo L. Differentiated thyroid carcinoma in children and adolescents: a 37-year experience in 85 patients. J Nucl Med. 1997;38(5):669–75.
CAS
PubMed
Google Scholar
Sassolas G, Hafdi-Nejjari Z, Ferraro A, Decaussin-Petrucci M, Rousset B, Borson-Chazot F, et al. Oncogenic alterations in papillary thyroid cancers of young patients. Thyroid. 2012;22(1):17–26.
Article
CAS
PubMed
Google Scholar
Hod N, Hagag P, Baumer M, Sandbank J, Horne T. Differentiated thyroid carcinoma in children and young adults: evaluation of response to treatment. Clin Nucl Med. 2005;30(6):387–90.
Article
PubMed
Google Scholar
Schonfeld SJ, Lee C, Berrington de Gonzalez A. Medical exposure to radiation and thyroid cancer. Clin Oncol (R Coll Radiol). 2011;23(4):244–50.
Article
CAS
Google Scholar
Fridman MV, Savva NN, Krasko OV, Zborovskaya AA, Mankovskaya SV, Schmid KW, et al. Clinical and pathologic features of ‘sporadic’ papillary thyroid carcinoma registered in 2005-2008 years in children and adolescents of Belarus. Thyroid. 2012;22(10):1016-24.
Manolio TA, Collins FS. The HapMap and genome-wide association studies in diagnosis and therapy. Annu Rev Med. 2009;60:443–56.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A. 2009;106(23):9362–7.
Article
CAS
PubMed
PubMed Central
Google Scholar
Mackay TF, Moore JH. Why epistasis is important for tackling complex human disease genetics. Genome Med. 2014;6(6):42.
Article
PubMed Central
Google Scholar
Musani SK, Shriner D, Liu N, Feng R, Coffey CS, Yi N, et al. Detection of gene x gene interactions in genome-wide association studies of human population data. Hum Hered. 2007;63(2):67–84.
Article
CAS
PubMed
Google Scholar
Ritchie MD, Hahn LW, Roodi N, Bailey LR, Dupont WD, Parl FF, et al. Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet. 2001;69(1):138–47.
Article
CAS
PubMed
PubMed Central
Google Scholar
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007;81(3):559–75.
Article
CAS
PubMed
PubMed Central
Google Scholar
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet. 2006;38(8):904–9.
Article
CAS
PubMed
Google Scholar
Clarke GM, Anderson CA, Pettersson FH, Cardon LR, Morris AP, Zondervan KT. Basic statistical analysis in genetic case–control studies. Nat Protoc. 2011;6(2):121–33.
Article
CAS
PubMed
PubMed Central
Google Scholar
Benjamini Y, Drai D, Elmer G, Kafkafi N, Golani I. Controlling the false discovery rate in behavior genetics research. Behav Brain Res. 2001;125(1-2):279–84.
Article
CAS
PubMed
Google Scholar
de Bakker PI, Yelensky R, Pe’er I, Gabriel SB, Daly MJ, Altshuler D. Efficiency and power in genetic association studies. Nat Genet. 2005;37(11):1217–23.
Article
PubMed
Google Scholar
González CYB M, F Salavert, R, Sánchez, J, Dopazo, Medina I. Multicore and Cloud-Based Solutions for Genomic Variant Analysis. In: Euro-Par 2012: Parallel Processing Workshops Lecture Notes in Computer Science vol. 7640; Springer, Berlin 2013: 273–284.
da Huang W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 2009;4(1):44–57.
Article
CAS
Google Scholar
Bulusu KC, Tym JE, Coker EA, Schierz AC, Al-Lazikani B. canSAR: updated cancer research and drug discovery knowledgebase. Nucleic Acids Res. 2014;42(Database issue):D1040–1047.
Article
CAS
PubMed
Google Scholar
Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D, et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res. 2011;39(Database issue):D945–950.
Article
CAS
PubMed
Google Scholar
Stelzer G, Dalah I, Stein TI, Satanower Y, Rosen N, Nativ N, et al. In-silico human genomics with GeneCards. Hum Genomics. 2011;5(6):709–17.
Article
CAS
PubMed
PubMed Central
Google Scholar
Warde-Farley D, Donaldson SL, Comes O, Zuberi K, Badrawi R, Chao P, et al. The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function. Nucleic Acids Res. 2010;38(Web Server issue):W214–220.
Article
CAS
PubMed
PubMed Central
Google Scholar
Uhlen M, Fagerberg L, Hallstrom BM, Lindskog C, Oksvold P, Mardinoglu A, et al. Proteomics. Tissue-based map of the human proteome. Science. 2015;347(6220):1260419.
Article
PubMed
Google Scholar
Barrett T, Wilhite SE, Ledoux P, Evangelista C, Kim IF, Tomashevsky M, et al. NCBI GEO: archive for functional genomics data sets--update. Nucleic Acids Res. 2013;41(Database issue):D991–995.
Article
CAS
PubMed
Google Scholar
Gaudet P, Michel PA, Zahn-Zabal M, Cusin I, Duek PD, Evalet O, et al. The neXtProt knowledgebase on human proteins: current status. Nucleic Acids Res. 2015;43(Database issue):D764–770.
Article
PubMed
Google Scholar
Xie C, Yuan J, Li H, Li M, Zhao G, Bu D, et al. NONCODEv4: exploring the world of long non-coding RNA genes. Nucleic Acids Res. 2014;42(Database issue):D98–103.
Article
CAS
PubMed
Google Scholar
Bleda M, Tarraga J, de Maria A, Salavert F, Garcia-Alonso L, Celma M, et al. CellBase, a comprehensive collection of RESTful web services for retrieving relevant biological information from heterogeneous sources. Nucleic Acids Res. 2012;40(Web Server issue):W609–614.
Article
CAS
PubMed
PubMed Central
Google Scholar
Derks S, Cleven AH, Melotte V, Smits KM, Brandes JC, Azad N, van Criekinge W, de Bruine AP, Herman JG, van Engeland M: Emerging evidence for CHFR as a cancer biomarker: from tumor biology to precision medicine. Cancer Metastasis Rev 2013.
Holley CL, Topkara VK. An introduction to small non-coding RNAs: miRNA and snoRNA. Cardiovasc Drugs Ther. 2011;25(2):151–9.
Article
CAS
PubMed
Google Scholar
Frasca F, Rustighi A, Malaguarnera R, Altamura S, Vigneri P, Del Sal G, et al. HMGA1 inhibits the function of p53 family members in thyroid cancer cells. Cancer Res. 2006;66(6):2980–9.
Article
CAS
PubMed
Google Scholar
Zou M, Baitei EY, Alzahrani AS, Al-Mohanna F, Farid NR, Meyer B, et al. Oncogenic activation of MAP kinase by BRAF pseudogene in thyroid tumors. Neoplasia. 2009;11(1):57–65.
Article
CAS
PubMed
PubMed Central
Google Scholar
Alonso R, Salavert F, Garcia-Garcia F, Carbonell-Caballero J, Bleda M, Garcia-Alonso L, et al. Babelomics 5.0: functional interpretation for new generations of genomic data. Nucleic Acids Res. 2015;43(W1):W117–121.
Article
PubMed
PubMed Central
Google Scholar
Arnaldi LA, Borra RC, Maciel RM, Cerutti JM. Gene expression profiles reveal that DCN, DIO1, and DIO2 are underexpressed in benign and malignant thyroid tumors. Thyroid. 2005;15(3):210–21.
Article
CAS
PubMed
Google Scholar
Binzak BA, Wevers RA, Moolenaar SH, Lee YM, Hwu WL, Poggi-Bach J, et al. Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency. Am J Hum Genet. 2001;68(4):839–47.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bell A, Bell D, Weber RS, El-Naggar AK. CpG island methylation profiling in human salivary gland adenoid cystic carcinoma. Cancer. 2011;117(13):2898–909.
Article
CAS
PubMed
PubMed Central
Google Scholar
He H, Li W, Liyanarachchi S, Jendrzejewski J, Srinivas M, Davuluri RV, et al. Genetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR and a novel lincRNA gene, PTCSC2. J Clin Endocrinol Metab. 2014;100(1):E164–72. doi:10.1210/jc.2014-2147.
Article
PubMed Central
Google Scholar
Wang Y, Guo Q, Zhao Y, Chen J, Wang S, Hu J, et al. BRAF-activated long non-coding RNA contributes to cell proliferation and activates autophagy in papillary thyroid carcinoma. Oncol Lett. 2014;8(5):1947–52.
PubMed
PubMed Central
Google Scholar
Fernandez RM, Bleda M, Luzon-Toro B, Garcia-Alonso L, Arnold S, Sribudiani Y, et al. Pathways systematically associated to Hirschsprung’s disease. Orphanet J Rare Dis. 2013;8(1):187.
Article
PubMed
PubMed Central
Google Scholar