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Table 4 Analyses by DAVID and GeneMANIA of the five significant genes found in jPTC by MDR

From: Identification of epistatic interactions through genome-wide association studies in sporadic medullary and juvenile papillary thyroid carcinomas

  CHST8 DIO1 DMGDH LOXL1 PXDNL
MDR Analyses RP11-648k4.2 RP11-648k4.2 RP11-648k4.2 RP11-648k4.2 RP11-648k4.2
Interacting genes according to scientific literature - DIO2 - - -
Interacting genes according to DAVID HS2ST1, TMEM132C, TMEM182 - - - -
Interactions Analyses by GeneMANIA Co-expression - TPO, PXDNL, DMGDH DIO1 - DIO1
Co-localization - TPO, DIO2 - - -
Genetic interactions ANKRD44, NNT NNT - ANKRD44, TPO -
Shared protein domain HS2ST1 DIO2 - - TPO