Table 4 Analyses by DAVID and GeneMANIA of the five significant genes found in jPTC by MDR
CHST8 | DIO1 | DMGDH | LOXL1 | PXDNL | ||
|---|---|---|---|---|---|---|
MDR Analyses | RP11-648k4.2 | RP11-648k4.2 | RP11-648k4.2 | RP11-648k4.2 | RP11-648k4.2 | |
Interacting genes according to scientific literature | - | DIO2 | - | - | - | |
Interacting genes according to DAVID | HS2ST1, TMEM132C, TMEM182 | - | - | - | - | |
Interactions Analyses by GeneMANIA | Co-expression | - | TPO, PXDNL, DMGDH | DIO1 | - | DIO1 |
Co-localization | - | TPO, DIO2 | - | - | - | |
Genetic interactions | ANKRD44, NNT | NNT | - | ANKRD44, TPO | - | |
Shared protein domain | HS2ST1 | DIO2 | - | - | TPO | |