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Table 1 Top 10 of the highest priority genes according to the criterion 6 calculated as the average value of five criteria

From: Prioritization of genes involved in endothelial cell apoptosis by their implication in lymphedema using an analysis of associative gene networks with ANDSystem

Gene Symbol

Protein name

Gene Id

1

2

3

4 A

4 B

5

6

ToppGene

Endeavour

GO BP

Gene CTC

Protein CTC

Comorbid

Average

KDR a

Vascular Endothelial Growth Factor Receptor 2

3791

1

1

2

1

4

11

1

TNF

Tumor Necrosis Factor alpha

7124

20

7

32

2

1

1

2

TEK

TEK Receptor Tyrosine Kinase

7010

2

5

4

19,5

11,5

27,5

3

BMPR2

Bone Morphogenetic Protein Receptor Type 2

659

15

12

25

9

10

18,5

4

SERPINE1

Serpin Family E Member 1

5054

10

27

36,5

9

11,5

3

5

IL10

Interleukin 10

3586

19

26

44

5,5

3

3

6

CD40LG

CD40 Ligand

959

29

31

20

7

5

11

7

CCL2

C-C Motif Chemokine Ligand 2

6347

6

43

46

5,5

6

3

8

FASLG

Fas Ligand

356

7

9

40

19,5

27,5

11

9

ABL1

ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase

25

4

4

42

9

7,5

49

10

  1. aControl gene with known associations with lymphedema