Fig. 2

Experimental validation of predicted miRNAs. a Cell proliferation assays in human lip fibroblasts treated with the indicated mimics of miRNAs. Negative control (control, light blue), miR-369-3p (orange), miR-655-3p (gray), miR-374a-3p (yellow), miR-374b-3p (blue), miR-497-5p (light green), and miR-124-3p (dark blue). *** p < 0.001. b Quantitative RT-PCR for the indicated genes after treatment with negative control (light blue) or miR-655-3p mimic (orange). * p < 0.05, ** p < 0.01, *** p < 0.001. c Quantitative RT-PCR for the indicated genes after treatment with negative control (light blue) or miR-497-5p mimic (orange). * p < 0.05, ** p < 0.01, *** p < 0.001