Table 4 Genotype and allele distributions between responders and non-responders of PPARD rs2016520 and NOS1AP rs12742393 variants (n = 60)
PPARD rs2016520 | Genotype | P value | Allele frequency | P value | |||
|---|---|---|---|---|---|---|---|
TT | TC | CC | T | C | |||
Responder (%) | 19 (54.29%) | 11 (47.83%) | 1 (50.00%) | 49 (52.69%) | 13 (48.15%) | ||
Non-responder (%) | 16 (45.71%) | 12 (52.17%) | 1 (50.00%) | 0.964 | 44 (47.31%) | 14 (51.85%) | 0.678 |
NOS1AP rs12742393 | AA | AC | CC | A | C | ||
Responder (%) | 17 (70.83%) | 12 (44.44%) | 2 (22.22%) | 46 (61.33%) | 16 (35.56%) | ||
Non-responder (%) | 7 (29.17%) | 1 5 (55.56%) | 7 (77.78%) | 0.027 | 29 (38.67%) | 29 (64.44%) | 0.006 |