SNP | Model | Genotype | Frequency | Unadjusted | Adjusted | |||
---|---|---|---|---|---|---|---|---|
Cases (500) | Controls (500) | OR (CI 95%) | P value | OR (CI 95%) | P value | |||
rs2241766 | Over dominant | GT | 0.81 | 0.25 | 12.46 (9.23–16.83) | 1.71 × 10–73 | 13.76 (9.39–20.1) | 2.47 × 10–51 |
TT-GG | 0.19 | 0.75 | – | – | – | – | ||
rs6494730 | Over dominant | GT | 0.65 | 0.31 | 4.17 (3.2–5.43) | 7.94 × 10–28 | 3.73 (2.69–5.16) | 5.19 × 10–16 |
GG-TT | 0.35 | 0.69 | – | – | – | – | ||
rs1799817 | Log-additive | – | – | – | 0.51 (0.4–0.65) | 1.63 × 10–08 | 0.53 (0.39–0.71) | 2.35 × 10–05 |
rs2059806 | – | – | – | 1.35 (1.14–1.61) | 0.0006 | 1.4 (1.13–1.74) | 0.0019 | |
rs7248104* | Recessive | AA | 0.20 | 0.15 | 1.38 (0.99–1.92) | 0.050 | 1.28 (1.03–1.59) | 0.027 |
GG-GA | 0.80 | 0.85 | – | – | – | – | ||
rs11745088 | Log-additive | – | – | – | 0.27 (0.14–0.54) | 4.85 × 10–05 | 0.32 (0.14–0.71) | 0.003 |
rs9939609 | Dominant | AT-AA | 0.58 | 0.44 | 1.74 (1.36–2.24) | 1.23 × 10–05 | 1.77 (1.29–2.42) | 0.0003 |
TT | 0.42 | 0.56 | – | – | – | – | ||
rs9940128 | Log-additive | – | – | – | 1.31 (1.10–1.57) | 0.002 | 1.21 (0.97–1.51) | 0.089# |
rs1421085 | Dominant | TC-CC | 0.64 | 0.55 | 1.43 (1.11–1.84) | 0.005 | 1.35 (0.98–1.85) | 0.062# |
TT | 0.36 | 0.45 | – | – | – | – | ||
rs17817449 | Log-additive | – | – | – | 1.23 (1.02–1.49) | 0.029 | 1.21 (0.96–1.54) | 0.109# |
rs8050136 | Log-additive | – | – | – | 1.23 (1.02–1.49) | 0.030 | 1.23 (0.97–1.56) | 0.080# |
rs12584136 | Over dominant | CA | 0.05 | 0.09 | 0.52 (0.31–0.87) | 0.011 | 0.54 (0.29–1.03) | 0.054# |
CC-AA | 0.95 | 0.91 | – | – | – | – | ||
rs1805097 | Log-additive | – | – | – | 2.01 (1.08–3.74) | 0.043 | 1.51 (0.71–3.21) | 0.287# |
rs1805094 | Recessive | CC | 0.99 | 0.98 | 0.20 (0.04–0.9) | 0.015 | 0.28 (0.05–1.60) | 0.115# |
GG-GC | 0.01 | 0.02 | – | – | – | – | ||
rs3802457 | Log-additive | – | – | – | 0.67 (0.48–0.93) | 0.017 | 0.73 (0.48–1.1) | 0.131# |
rs2161829 | Log-additive | – | – | – | 1.16 (0.98–1.39) | 0.089# | 1.22 (0.98–1.51) | 0.07# |