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Table 3 Results of pair wise gene–gene interactions using logistic regression analysis

From: The genetic susceptibility profile of type 2 diabetes and reflection of its possible role related to reproductive dysfunctions in the southern Indian population of Hyderabad

Gene–Gene SNP–SNP OR P value
LEPR-INSR rs1137101*-rs7248104 1.74 1.89 × 10–05
LOC107985940-INSIG2 rs7566605*-rs2161829 1.87 1.13 × 10–05
ADIPOQ rs2241766-rs1501299* 3.13 5.49 × 10–05
ADIPOQ-INSR rs2241766-rs1799817 0.15 1.24 × 10–12
DENND1A rs10818854* rs2479106* 0.20 1.72 × 10–05
INSR rs1799817-rs2059806 2.42 1.91 × 10–06
rs1865434*-rs7987237* 0.37 2.39 × 10–05
FTO rs9940128-rs1421085 0.50 3.92 × 10–07
rs1421085-rs17817449 0.40 9.96 × 10–11
rs1421085-rs8050136 0.40 1.92 × 10–10
rs1421085-rs9939609 0.40 3.77 × 10–10
  1. *SNPs only associated at interaction level but not at allelic association