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Table 3 Multivariate logistic regression for TP and some SNPs during acute and delayed phases

From: A randomized trial evaluating the association between related gene polymorphism and nausea and vomiting induced by cisplatin multi-day chemotherapy

Clinical factors

Acute Phase

Delayed Phase

OR

95% CI

P value

OR

95% CI

P value

Group

0.649

0.189-2.231

0.493

0.14

0.015-1.337

0.088

Gender

0.661

0.191-2.292

0.514

0.123

0.0040-4.002

0.238

HTR3A

rs1062613

CC vs. Non-CC

   

1.06

0.019-58.503

0.977

rs1176719

GG vs. Non-GG

1.355

0.156-11.800

0.783

0.076

0.001-9.345

0.293

rs2276303

GG vs. Non-GG

0.294

0.027-3.193

0.315

   

HTR3B

rs45460698

-100_-102AAG deletion variants vs. wild type

   

1.297

0.092-18.193

0.847

rs7943062

GG vs. Non-GG

   

0.004

0.000-0.221

0.007

HTR3C

rs6766410

CC vs. Non-CC

   

41645.423

19.065-90971913.963

0.007

ERCC1

rs3212986

CC vs. Non-CC

   

22.888

0.575-910.550

0.096

ERCC4

rs744154

CC vs. Non-CC

   

19,150,000,000

0.000-.

1

MTHFR

rs1801131

TT vs. Non-TT

0.263

0.074-0.926

0.038

0.005

0.000-0.807

0.041