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Volume 10 Supplement 1

Selected articles from the 6th Translational Bioinformatics Conference (TBC 2016): medical genomics


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Je Ju Island, Korea15-17 October 2016

Edited by Ju Han Kim and Maricel Kann

Related articles have been published as a supplement to BMC Medical Informatics and Decision Making

  1. Content type: Research

    Transcriptome analytic tools are commonly used across patient cohorts to develop drugs and predict clinical outcomes. However, as precision medicine pursues more accurate and individualized treatment decisions...

    Authors: Qike Li, A. Grant Schissler, Vincent Gardeux, Ikbel Achour, Colleen Kenost, Joanne Berghout, Haiquan Li, Hao Helen Zhang and Yves A. Lussier

    Citation: BMC Medical Genomics 2017 10(Suppl 1):27

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  2. Content type: Research

    Many genetic diseases are caused by mutations in non-coding regions of the genome. These mutations are frequently found in enhancer sequences, causing disruption to the regulatory program of the cell. Enhancer...

    Authors: Julia Herman-Izycka, Michal Wlasnowolski and Bartek Wilczynski

    Citation: BMC Medical Genomics 2017 10(Suppl 1):34

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  3. Content type: Research

    Complex diseases involve many genes, and these genes are often associated with several different illnesses. Disease similarity measurement can be based on shared genotype or phenotype. Quantifying relationship...

    Authors: Matthew B. Carson, Cong Liu, Yao Lu, Caiyan Jia and Hui Lu

    Citation: BMC Medical Genomics 2017 10(Suppl 1):26

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  4. Content type: Research

    Aspirin Exacerbated Respiratory Disease (AERD) is a chronic medical condition that encompasses asthma, nasal polyposis, and hypersensitivity to aspirin and other non-steroidal anti-inflammatory drugs. Several ...

    Authors: Sehee Wang, Hyun-hwan Jeong, Dokyoon Kim, Kyubum Wee, Hae-Sim Park, Seung-Hyun Kim and Kyung-Ah Sohn

    Citation: BMC Medical Genomics 2017 10(Suppl 1):31

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  5. Content type: Research

    The APOE ε4 allele is the most significant common genetic risk factor for late-onset Alzheimer’s disease (LOAD). The region surrounding APOE on chromosome 19 has also shown consistent association with LOAD. Howev...

    Authors: Kwangsik Nho, Sungeun Kim, Emrin Horgusluoglu, Shannon L. Risacher, Li Shen, Dokyoon Kim, Seunggeun Lee, Tatiana Foroud, Leslie M. Shaw, John Q. Trojanowski, Paul S. Aisen, Ronald C. Petersen, Clifford R. Jack Jr., Michael W. Weiner, Robert C. Green, Arthur W. Toga…

    Citation: BMC Medical Genomics 2017 10(Suppl 1):29

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  6. Content type: Research

    Breast cancer is a complex disease in which different genomic patterns exists depending on different subtypes. Recent researches present that multiple subtypes of breast cancer occur at different rates, and pl...

    Authors: Garam Lee, Lisa Bang, So Yeon Kim, Dokyoon Kim and Kyung-Ah Sohn

    Citation: BMC Medical Genomics 2017 10(Suppl 1):28

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  7. Content type: Research

    One of the fundamental challenges in cancer is to detect the regulators of gene expression changes during cancer progression. Through transcriptional silencing of critical cancer-related genes, epigenetic chan...

    Authors: Manu Shivakumar, Younghee Lee, Lisa Bang, Tullika Garg, Kyung-Ah Sohn and Dokyoon Kim

    Citation: BMC Medical Genomics 2017 10(Suppl 1):30

    Published on: