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Volume 11 Supplement 3

Selected articles from the 7th Translational Bioinformatics Conference (TBC 2017): medical genomics


Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. The articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

Los Angeles, CA, USA29 September - 01 October 2017

Conference website

Edited by Dokyoon Kim and Marylyn Ritchie.

Articles from this conference have also been published as a supplement in BMC Medical Informatics and Decision Making.

  1. Content type: Research

    Understanding the effect of human genetic variations on disease can provide insight into phenotype-genotype relationships, and has great potential for improving the effectiveness of personalized medicine. Whil...

    Authors: Ann G. Cirincione, Kaylyn L. Clark and Maricel G. Kann

    Citation: BMC Medical Genomics 2018 11(Suppl 3):75

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  2. Content type: Research

    High levels of triglycerides (TG ≥200 mg/dL) are an emerging risk factor for cardiovascular disease. Conversely, very low levels of TG are associated with decreased risk for cardiovascular disease. Precision m...

    Authors: Dana C. Crawford, Nicole A. Restrepo, Kirsten E. Diggins, Eric Farber-Eger and Quinn S. Wells

    Citation: BMC Medical Genomics 2018 11(Suppl 3):66

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  3. Content type: Research

    Large-scale collaborative precision medicine initiatives (e.g., The Cancer Genome Atlas (TCGA)) are yielding rich multi-omics data. Integrative analyses of the resulting multi-omics data, such as somatic mutat...

    Authors: Yasser EL-Manzalawy, Tsung-Yu Hsieh, Manu Shivakumar, Dokyoon Kim and Vasant Honavar

    Citation: BMC Medical Genomics 2018 11(Suppl 3):71

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  4. Content type: Research

    Integrative analysis on multi-omics data has gained much attention recently. To investigate the interactive effect of gene expression and DNA methylation on cancer, we propose a directed random walk-based appr...

    Authors: So Yeon Kim, Tae Rim Kim, Hyun-Hwan Jeong and Kyung-Ah Sohn

    Citation: BMC Medical Genomics 2018 11(Suppl 3):68

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  5. Content type: Research

    Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases that causes problems related to brain function. To some extent it is understood on a molecular level how AD arises, however there a...

    Authors: Jason E. Miller, Manu K. Shivakumar, Younghee Lee, Seonggyun Han, Emrin Horgousluoglu, Shannon L. Risacher, Andrew J. Saykin, Kwangsik Nho and Dokyoon Kim

    Citation: BMC Medical Genomics 2018 11(Suppl 3):76

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  6. Content type: Research

    RNA-seq is the most commonly used sequencing application. Not only does it measure gene expression but it is also an excellent media to detect important structural variants such as single nucleotide variants (...

    Authors: Naresh Prodduturi, Aditya Bhagwate, Jean-Pierre A. Kocher and Zhifu Sun

    Citation: BMC Medical Genomics 2018 11(Suppl 3):67

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  7. Content type: Research

    Glaucoma is a leading cause of blindness in developed countries. Primary open-angle glaucoma (POAG), the most prevalent clinical subtype of glaucoma in the United States, affects African Americans at a higher ...

    Authors: Nicole A. Restrepo, Sarah M. Laper, Eric Farber-Eger and Dana C. Crawford

    Citation: BMC Medical Genomics 2018 11(Suppl 3):70

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