Skip to main content

Volume 6 Supplement 2

Selected articles from the Second Annual Translational Bioinformatics Conference (TBC 2012)

Research

Edited by Ju Han Kim, Maricel Kann and Jessica Tenenbaum

Publication of this supplement has not been supported by any external sponsorship. Information about the funding for publication costs can be found in the Declarations section of each article.

Second Annual Translational Bioinformatics Conference (TBC 2012). Go to conference site.

Jeju Island, Korea13-16 October 2012

  1. High-throughput (HT) RNA interference (RNAi) screens are increasingly used for reverse genetics and drug discovery. These experiments are laborious and costly, hence sample sizes are often very small. Powerful...

    Authors: Mark A van de Wiel, Renée X de Menezes, Ellen Siebring-van Olst and Victor W van Beusechem
    Citation: BMC Medical Genomics 2013 6(Suppl 2):S1
  2. Genes do not act in isolation but instead as part of complex regulatory networks. To understand how breast tumors adapt to the presence of the drug letrozole, at the molecular level, it is necessary to conside...

    Authors: Nadia M Penrod and Jason H Moore
    Citation: BMC Medical Genomics 2013 6(Suppl 2):S2
  3. Using annotations to the articles in MEDLINE®/PubMed®, over six thousand chemical compounds with pharmacological actions have been tracked since 1996. Medical Subject Heading Over-representation Profiles (MeSHOPs...

    Authors: Warren A Cheung, BF Francis Ouellette and Wyeth W Wasserman
    Citation: BMC Medical Genomics 2013 6(Suppl 2):S3
  4. Gene expression-based prostate cancer gene signatures of poor prognosis are hampered by lack of gene feature reproducibility and a lack of understandability of their function. Molecular pathway-level mechanism...

    Authors: James L Chen, Alexander Hsu, Xinan Yang, Jianrong Li, Younghee Lee, Gurunadh Parinandi, Haiquan Li and Yves A Lussier
    Citation: BMC Medical Genomics 2013 6(Suppl 2):S4
  5. It was previously reported that an association analysis based on haplotype clusters increased power over single-locus tests, and that another association test based on diplotype trend regression analysis outpe...

    Authors: Sunshin Kim, KyungChae Park, Chol Shin, Nam H Cho, Jeong-Jae Ko, InSong Koh and KyuBum Kwack
    Citation: BMC Medical Genomics 2013 6(Suppl 2):S5
  6. With the recent decreasing cost of genome sequence data, there has been increasing interest in rare variants and methods to detect their association to disease. We developed BioBin, a flexible collapsing metho...

    Authors: Carrie B Moore, John R Wallace, Alex T Frase, Sarah A Pendergrass and Marylyn D Ritchie
    Citation: BMC Medical Genomics 2013 6(Suppl 2):S6
  7. Type 1 diabetes (T1D) is a complex disease and harmful to human health, and most of the existing biomarkers are mainly to measure the disease phenotype after the disease onset (or drastic deterioration). Until...

    Authors: Xiaoping Liu, Rui Liu, Xing-Ming Zhao and Luonan Chen
    Citation: BMC Medical Genomics 2013 6(Suppl 2):S8
  8. Congenital muscular torticollis (CMT) is characterized by thickening and/or tightness of the unilateral sternocleidomastoid muscle (SCM), ending up with torticollis. Our aim was to identify differentially expr...

    Authors: Shin-Young Yim, Dukyong Yoon, Myong Chul Park, Il Jae Lee, Jang-Hee Kim, Myung Ae Lee, Kyu-Sung Kwack, Jan-Dee Lee, Jeong-Hun Lee, Euy-Young Soh, Young-In Na, Rae Woong Park, KiYoung Lee and Jae-Bum Jun
    Citation: BMC Medical Genomics 2013 6(Suppl 2):S10

Annual Journal Metrics

Peer-review Terminology

  • The following summary describes the peer review process for this journal:

    Identity transparency: Single anonymized

    Reviewer interacts with: Editor

    Review information published: Review reports. Reviewer Identities reviewer opt in. Author/reviewer communication

    More information is available here

Sign up for article alerts and news from this journal