Torabi A, Cleland JG, Khan NK, Loh PH, Clark AL, Alamgir F, Caplin JL, Rigby AS, Goode K: The timing of development and subsequent clinical course of heart failure after a myocardial infarction. Eur Heart J. 2008, 29: 859-870. 10.1093/eurheartj/ehn096.
Article
PubMed
Google Scholar
Ezekowitz JA, Kaul P, Bakal JA, Armstrong PW, Welsh RC, McAlister FA: Declining in-hospital mortality and increasing heart failure incidence in elderly patients with first myocardial infarction. J Am Coll Cardiol. 2009, 53: 13-20. 10.1016/j.jacc.2008.08.067.
Article
PubMed
Google Scholar
Schocken DD, Benjamin EJ, Fonarow GC, Krumholz HM, Levy D, Mensah GA, Narula J, Shor ES, Young JB, Hong Y: Prevention of heart failure: a scientific statement from the American Heart Association Councils on Epidemiology and Prevention, Clinical Cardiology, Cardiovascular Nursing, and High Blood Pressure Research; Quality of Care and Outcomes Research Interdisciplinary Working Group; and Functional Genomics and Translational Biology Interdisciplinary Working Group. Circulation. 2008, 117: 2544-2565. 10.1161/CIRCULATIONAHA.107.188965.
Article
PubMed
Google Scholar
de Kam PJ, Nicolosi GL, Voors AA, van den Berg MP, Brouwer J, van Veldhuisen DJ, Barlera S, Maggioni AP, Giannuzzi P, Temporelli PL, Latini R, van Gilst WH: Prediction of 6 months left ventricular dilatation after myocardial infarction in relation to cardiac morbidity and mortality. Application of a new dilatation model to GISSI-3 data. Eur Heart J. 2002, 23: 536-542. 10.1053/euhj.2001.2820.
Article
CAS
PubMed
Google Scholar
Azuaje F: What does systems biology mean for biomarker discovery?. Exp Opin Med Diagn. 2009, 4: 1-10.
Article
Google Scholar
Azuaje F, Devaux Y, Wagner DR: Integrative pathway-centric modeling of ventricular dysfunction after myocardial infarction. PLoS One. 2010, 5: e9661-10.1371/journal.pone.0009661.
Article
PubMed
PubMed Central
Google Scholar
Devaux Y, Azuaje F, Vausort M, Yvorra C, Wagner DR: Integrated protein network and microarray analysis to identify potential biomarkers after myocardial infarction. Funct Integr Genomics. 2010, 10: 329-337. 10.1007/s10142-010-0169-0.
Article
CAS
PubMed
Google Scholar
Nepomuceno-Chamorro I, Azuaje F, Devaux Y, Nazarov PV, Muller A, Aguilar-Ruiz JS, Wagner DR: Prognostic transcriptional association networks: a new supervised approach based on regression trees. Bioinformatics. 2011, 27: 252-258. 10.1093/bioinformatics/btq645.
Article
CAS
PubMed
Google Scholar
Gerber BL, Rochitte CE, Melin JA, McVeigh ER, Bluemke DA, Wu KC, Becker LC, Lima JA: Microvascular obstruction and left ventricular remodeling early after acute myocardial infarction. Circulation. 2000, 101: 2734-2741.
Article
CAS
PubMed
Google Scholar
Bolognese L, Carrabba N, Parodi G, Santoro GM, Buonamici P, Cerisano G, Antoniucci D: Impact of microvascular dysfunction on left ventricular remodeling and long-term clinical outcome after primary coronary angioplasty for acute myocardial infarction. Circulation. 2004, 109: 1121-1126. 10.1161/01.CIR.0000118496.44135.A7.
Article
PubMed
Google Scholar
Nijveldt R, Beek AM, Hirsch A, Stoel MG, Hofman MB, Umans VA, Algra PR, Twisk JW, van Rossum AC: Functional recovery after acute myocardial infarction: comparison between angiography, electrocardiography, and cardiovascular magnetic resonance measures of microvascular injury. J Am Coll Cardiol. 2008, 52: 181-189. 10.1016/j.jacc.2008.04.006.
Article
PubMed
Google Scholar
Abdollahi A, Schwager C, Kleeff J, Esposito I, Domhan S, Peschke P, Hauser K, Hahnfeldt P, Hlatky L, Debus J, Peters JM, Friess H, Folkman J, Huber PE: Transcriptional network governing the angiogenic switch in human pancreatic cancer. Proc Natl Acad Sci USA. 2007, 104: 12890-12895. 10.1073/pnas.0705505104.
Article
CAS
PubMed
PubMed Central
Google Scholar
Azuaje F, Devaux Y, Vausort M, Yvorra C, Wagner DR: Transcriptional networks characterize ventricular dysfunction after myocardial infarction: A proof-of-concept investigation. J Biomed Inform. 2010, 43: 812-819. 10.1016/j.jbi.2010.05.012.
Article
PubMed
Google Scholar
Le Brigand K, Russell R, Moreilhon C, Rouillard JM, Jost B, Amiot F, Magnone V, Bole-Feysot C, Rostagno P, Virolle V, Defamie V, Dessen P, Williams G, Lyons P, Rios G, Mari B, Gulari E, Kastner P, Gidrol X, Freeman TC, Barbry P: An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes. Nucleic Acids Res. 2006, 34: e87-10.1093/nar/gkl485.
Article
PubMed
Google Scholar
Margulies KB, Bednarik DP, Dries DL: Genomics, transcriptional profiling, and heart failure. J Am Coll Cardiol. 2009, 53: 1752-1759. 10.1016/j.jacc.2008.12.064.
Article
CAS
PubMed
PubMed Central
Google Scholar
Wingrove JA, Daniels SE, Sehnert AJ, Tingley W, M E, Rosenberger S, Buellesfeld L, Grube E, Newby LK, Ginsburg GS, Kraus WE: Correlation of Peripheral-Blood Gene Expression With the Extent of Coronary Artery Stenosis. Circ Cardiovasc Genet. 2008, 1: 31-38. 10.1161/CIRCGENETICS.108.782730.
Article
CAS
PubMed
Google Scholar
Cappuzzello C, Napolitano M, Arcelli D, Melillo G, Melchionna R, Di Vito L, Carlini D, Silvestri L, Brugaletta S, Liuzzo G, Crea F, Capogrossi MC: Gene expression profiles in peripheral blood mononuclear cells of chronic heart failure patients. Physiol Genomics. 2009, 38: 233-240. 10.1152/physiolgenomics.90364.2008.
Article
CAS
PubMed
Google Scholar
Almendral JL, Shick V, Rosendorff C, Atlas SA: Association between transforming growth factor-[beta]1 and left ventricular mass and diameter in hypertensive patients. J Am Soc Hypertens. 2010, 4: 135-141. 10.1016/j.jash.2010.02.007.
Article
CAS
PubMed
Google Scholar
Villar AV, Cobo M, Llano M, Montalvo C, Gonzalez-Vilchez F, Martin-Duran R, Hurle MA, Nistal JF: Plasma Levels of Transforming Growth Factor-Î21 Reflect Left Ventricular Remodeling in Aortic Stenosis. PLoS One. 2009, 4: e8476-10.1371/journal.pone.0008476.
Article
PubMed
PubMed Central
Google Scholar
Zethelius B, Berglund L, Sundstrom J, Ingelsson E, Basu S, Larsson A, Venge P, Arnlov J: Use of multiple biomarkers to improve the prediction of death from cardiovascular causes. N Engl J Med. 2008, 358: 2107-2116. 10.1056/NEJMoa0707064.
Article
CAS
PubMed
Google Scholar
Ware JH: The limitations of risk factors as prognostic tools. N Engl J Med. 2006, 355: 2615-2617. 10.1056/NEJMp068249.
Article
CAS
PubMed
Google Scholar
Heidecker B, Kasper EK, Wittstein IS, Champion HC, Breton E, Russell SD, Kittleson MM, Baughman KL, Hare JM: Transcriptomic biomarkers for individual risk assessment in new-onset heart failure. Circulation. 2008, 118: 238-246. 10.1161/CIRCULATIONAHA.107.756544.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zile MR, Desantis SM, Baicu CF, Stroud RE, Thompson SB, McClure CD, Mehurg SM, Spinale FG: Plasma Biomarkers That Reflect Determinants of Matrix Composition Identify the Presence of Left Ventricular Hypertrophy and Diastolic Heart Failure. Circ Heart Fail. 2011, 4: 246-256. 10.1161/CIRCHEARTFAILURE.110.958199.
Article
CAS
PubMed
PubMed Central
Google Scholar
Oemrawsingh RM, Lenderink T, Akkerhuis KM, Heeschen C, Baldus S, Fichtlscherer S, Hamm CW, Simoons ML, Boersma E: Multimarker risk model containing troponin-T, interleukin 10, myeloperoxidase and placental growth factor predicts long-term cardiovascular risk after non-ST-segment elevation acute coronary syndrome. Heart. 2011, 97: 1061-1066. 10.1136/hrt.2010.197392.
Article
CAS
PubMed
Google Scholar
Koitabashi N, Danner T, Zaiman AL, Pinto YM, Rowell J, Mankowski J, Zhang D, Nakamura T, Takimoto E, Kass DA: Pivotal role of cardiomyocyte TGF-beta signaling in the murine pathological response to sustained pressure overload. J Clin Invest. 2011, 126: 2301-2312.
Article
Google Scholar
Pepper MS: Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity. Cytokine Growth Factor Rev. 1997, 8: 21-43. 10.1016/S1359-6101(96)00048-2.
Article
CAS
PubMed
Google Scholar
Dobaczewski M, Chen W, Frangogiannis NG: Transforming growth factor (TGF)-[beta] signaling in cardiac remodeling. J Mol Cell Cardiol. 2011, 51: 600-606. 10.1016/j.yjmcc.2010.10.033.
Article
CAS
PubMed
Google Scholar
Ellmers LJ, Scott NJA, Medicherla S, Pilbrow AP, Bridgman PG, Yandle TG, Richards AM, Protter AA, Cameron VA: Transforming Growth Factor-{beta} Blockade Down-Regulates the Renin-Angiotensin System and Modifies Cardiac Remodeling after Myocardial Infarction. Endocrinology. 2008, 149: 5828-5834. 10.1210/en.2008-0165.
Article
CAS
PubMed
Google Scholar
Bujak M, Ren G, Kweon HJ, Dobaczewski M, Reddy A, Taffet G, Wang X-F, Frangogiannis NG: Essential Role of Smad3 in Infarct Healing and in the Pathogenesis of Cardiac Remodeling. Circulation. 2007, 116: 2127-2138. 10.1161/CIRCULATIONAHA.107.704197.
Article
CAS
PubMed
Google Scholar
Kapur NK: Transforming Growth Factor-Î2. Circ Heart Fail. 2011, 4: 5-7. 10.1161/CIRCHEARTFAILURE.110.960054.
Article
PubMed
Google Scholar
Mukherjee R, Rivers WT, Ruddy JM, Matthews RG, Koval CN, Plyler RA, Chang EI, Patel RK, Kern CB, Stroud RE, Spinale FG: Long-Term Localized High-Frequency Electric Stimulation Within the Myocardial Infarct: Effects on Matrix Metalloproteinases and Regional Remodeling. Circulation. 2010, 122: 20-32. 10.1161/CIRCULATIONAHA.110.936872.
Article
CAS
PubMed
PubMed Central
Google Scholar
Tan SM, Zhang Y, Connelly KA, Gilbert RE, Kelly DJ: Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction. Am J Physiol-Heart and Circ Physiol. 2010, 298: H1415-H1425. 10.1152/ajpheart.01048.2009.
Article
CAS
Google Scholar
Okada H, Takemura G, Kosai K-i, Li Y, Takahashi T, Esaki M, Yuge K, Miyata S, Maruyama R, Mikami A, Minatoguchi S, Fujiwara T, Fujiwara H: Postinfarction Gene Therapy Against Transforming Growth Factor-{beta} Signal Modulates Infarct Tissue Dynamics and Attenuates Left Ventricular Remodeling and Heart Failure. Circulation. 2005, 111: 2430-2437. 10.1161/01.CIR.0000165066.71481.8E.
Article
CAS
PubMed
Google Scholar
Hawinkels LJAC, ten Dijke P: Exploring anti-TGF-Î2 therapies in cancer and fibrosis. Growth Factors. 2011, 29: 140-152. 10.3109/08977194.2011.595411.
Article
CAS
PubMed
Google Scholar
Loeys BL, Chen J, Neptune ER, Judge DP, Podowski M, Holm T, Meyers J, Leitch CC, Katsanis N, Sharifi N, Xu FL, Myers LA, Spevak PJ, Cameron DE, De Backer J, Hellemans J, Chen Y, Davis EC, Webb CL, Kress W, Coucke P, Rifkin DB, De Paepe AM, Dietz HC: A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2. Nat Genet. 2005, 37: 275-281. 10.1038/ng1511.
Article
CAS
PubMed
Google Scholar
Loeys BL, Schwarze U, Holm T, Callewaert BL, Thomas GH, Pannu H, De Backer JF, Oswald GL, Symoens S, Manouvrier S, Roberts AE, Faravelli F, Greco MA, Pyeritz RE, Milewicz DM, Coucke PJ, Cameron DE, Braverman AC, Byers PH, De Paepe AM, Dietz HC: Aneurysm syndromes caused by mutations in the TGF-beta receptor. N Engl J Med. 2006, 355: 788-798. 10.1056/NEJMoa055695.
Article
CAS
PubMed
Google Scholar
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP: Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 2005, 102: 15545-15550. 10.1073/pnas.0506580102.
Article
CAS
PubMed
PubMed Central
Google Scholar
The Entrez-Gene Database. [http://www.ncbi.nlm.nih.gov/entrez]
Peri S, Navarro JD, Amanchy R, Kristiansen TZ, Jonnalagadda CK, Surendranath V, Niranjan V, Muthusamy B, Gandhi TK, Gronborg M, Ibarrola N, Deshpande N, Shanker K, Shivashankar HN, Rashmi BP, Ramya MA, Zhao Z, Chandrika KN, Padma N, Harsha HC, Yatish AJ, Kavitha MP, Menezes M, Choudhury DR, Suresh S, Ghosh N, Saravana R, Chandran S, Krishna S, Joy M, Anand SK, Madavan V, Joseph A, Wong GW, Schiemann WP, Constantinescu SN, Huang L, Khosravi-Far R, Steen H, Tewari M, Ghaffari S, Blobe GC, Dang CV, Garcia JG, Pevsner J, Jensen ON, Roepstorff P, Deshpande KS, Chinnaiyan AM, Hamosh A, Chakravarti A, Pandey A: Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res. 2003, 13: 2363-2371. 10.1101/gr.1680803.
Article
CAS
PubMed
PubMed Central
Google Scholar
Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T: Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003, 13: 2498-2504. 10.1101/gr.1239303.
Article
CAS
PubMed
PubMed Central
Google Scholar
Bader GD, Hogue CW: An automated method for finding molecular complexes in large protein interaction networks. BMC Bioinformatics. 2003, 4: 2-10.1186/1471-2105-4-2.
Article
PubMed
PubMed Central
Google Scholar
Maskali F, Franken PR, Poussier S, Tran N, Vanhove C, Boutley H, Le Gall H, Karcher G, Zannad F, Lacolley P, Marie PY: Initial infarct size predicts subsequent cardiac remodeling in the rat infarct model: an in vivo serial pinhole gated SPECT study. J Nucl Med. 2006, 47: 337-344.
PubMed
Google Scholar
Maskali F, Poussier S, Marie PY, Tran N, Antunes L, Olivier P, Plenat F, Maitrejean S, Zannad F, Karcher G: High-resolution simultaneous imaging of SPECT, PET, and MRI tracers on histologic sections of myocardial infarction. J Nucl Cardiol. 2005, 12: 229-230. 10.1016/j.nuclcard.2004.12.296.
Article
PubMed
Google Scholar
Poussier S, Maskali F, Tran N, Person C, Maureira P, Boutley H, Karcher G, Lacolley P, Regnault V, Fay R, Marie PY: ECG-triggered (18)F-fluorodeoxyglucose positron emission tomography imaging of the rat heart is dramatically enhanced by acipimox. Eur J Nucl Med Mol Imaging. 2010, 37: 1745-1750. 10.1007/s00259-010-1418-0.
Article
PubMed
Google Scholar
Germano G, Kiat H, Kavanagh PB, Moriel M, Mazzanti M, Su HT, Van Train KF, Berman DS: Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med. 1995, 36: 2138-2147.
CAS
PubMed
Google Scholar
Frank E, Hall M, Trigg L, Holmes G, Witten IH: Data mining in bioinformatics using Weka. Bioinformatics. 2004, 20: 2479-2481. 10.1093/bioinformatics/bth261.
Article
CAS
PubMed
Google Scholar