Volume 7 Supplement 1
Selected articles from the 3rd Translational Bioinformatics Conference (TBC/ISCB-Asia 2013)
Research
Edited by Ju Han Kim and Maricel Kann
Publication of this supplement has not been supported by sponsorship. Information about the source of funding for publication charges can be found in the individual articles. Articles have undergone the journal's standard review process for supplements. The Supplement Editors declare that they have no competing interests.
The 3rd Annual Translational Bioinformatics Conference (TBC/ISCB-Asia 2013). Go to conference site.
Seoul, Korea2-4 October 2013
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Citation: BMC Medical Genomics 2014 7(Suppl 1):I1
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Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study
Genome-wide transcriptome profiling generated by microarray and RNA-Seq often provides deregulated genes or pathways applicable only to larger cohort. On the other hand, individualized interpretation of transc...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S1 -
In Silicocancer cell versus stroma cellularity index computed from species-specific human and mouse transcriptome of xenograft models: towards accurate stroma targeting therapy assessment
The current state of the art for measuring stromal response to targeted therapy requires burdensome and rate limiting quantitative histology. Transcriptome measures are increasingly affordable and provide an o...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S2 -
Integrative analysis reveals disease-associated genes and biomarkers for prostate cancer progression
Prostate cancer is one of the most common complex diseases with high leading cause of death in men. Identifications of prostate cancer associated genes and biomarkers are thus essential as they can gain insigh...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S3 -
A coupling approach of a predictor and a descriptor for breast cancer prognosis
In cancer prognosis research, diverse machine learning models have applied to the problems of cancer susceptibility (risk assessment), cancer recurrence (redevelopment of cancer after resolution), and cancer s...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S4 -
Derivative component analysis for mass spectral serum proteomic profiles
As a promising way to transform medicine, mass spectrometry based proteomics technologies have seen a great progress in identifying disease biomarkers for clinical diagnosis and prognosis. However, there is a ...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S5 -
IGENT: efficient entropy based algorithm for genome-wide gene-gene interaction analysis
With the development of high-throughput genotyping and sequencing technology, there are growing evidences of association with genetic variants and complex traits. In spite of thousands of genetic variants disc...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S6 -
Predicting phenotypes of asthma and eczema with machine learning
There is increasing recognition that asthma and eczema are heterogeneous diseases. We investigated the predictive ability of a spectrum of machine learning methods to disambiguate clinical sub-groups of asthma...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S7 -
Identification of novel therapeutics for complex diseases from genome-wide association data
Human genome sequencing has enabled the association of phenotypes with genetic loci, but our ability to effectively translate this data to the clinic has not kept pace. Over the past 60 years, pharmaceutical c...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S8 -
GAMUT: GPU accelerated microRNA analysis to uncover target genes through CUDA-miRanda
Non-coding sequences such as microRNAs have important roles in disease processes. Computational microRNA target identification (CMTI) is becoming increasingly important since traditional experimental methods f...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S9 -
Integrated analysis of microRNA-target interactions with clinical outcomes for cancers
Clinical statement alone is not enough to predict the progression of disease. Instead, the gene expression profiles have been widely used to forecast clinical outcomes. Many genes related to survival have been...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S10 -
Effectively processing medical term queries on the UMLS Metathesaurus by layered dynamic programming
Mapping medical terms to standardized UMLS concepts is a basic step for leveraging biomedical texts in data management and analysis. However, available methods and tools have major limitations in handling quer...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S11 -
Automatic detection and resolution of measurement-unit conflicts in aggregated data
Measurement-unit conflicts are a perennial problem in integrative research domains such as clinical meta-analysis. As multi-national collaborations grow, as new measurement instruments appear, and as Linked Op...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S12 -
Comparison of warfarin therapy clinical outcomes following implementation of an automated mobile phone-based critical laboratory value text alert system
Computerized alert and reminder systems have been widely accepted and applied to various patient care settings, with increasing numbers of clinical laboratories communicating critical laboratory test values to...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S13 -
Differentially private distributed logistic regression using private and public data
Privacy protecting is an important issue in medical informatics and differential privacy is a state-of-the-art framework for data privacy research. Differential privacy offers provable privacy against attacker...
Citation: BMC Medical Genomics 2014 7(Suppl 1):S14
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Citation Impact 2023
Journal Impact Factor: 2.1
5-year Journal Impact Factor: 2.5
Source Normalized Impact per Paper (SNIP): 0.581
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